Vcam1 - vascular cell adhesion molecule 1 Gene

Also Known as CD106; Vcam-1

Species: Mus musculus

Gene Type: protein coding
Gene ID: 22329

Summary

Predicted to enable Integrin binding activity and primary amine oxidase activity. Acts upstream of or within several processes, including cellular response to glucose stimulus; chorio-allantoic fusion; and heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules. Located in apical plasma membrane. Is expressed in several structures, including brain; embryo mesenchyme; extraembryonic component; heart; and hemolymphoid system. Human ortholog(s) of this gene implicated in hypertension. Orthologous to human VCAM1 (vascular cell adhesion molecule 1). [provided by Alliance of Genome Resources, Apr 2022]

Vcam1 Products (1)

mRNA Protein Name
NM_011693.3 NP_035823.3 vascular cell adhesion protein 1 precursor

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
acts upstream of or within cell adhesion IDA
IDA: Inferred from direct assay
12021259 MGI
acts upstream of or within cellular response to glucose stimulus IDA
IDA: Inferred from direct assay
17670746 MGI
acts upstream of or within chorio-allantoic fusion IMP
IMP: Inferred from mutant phenotype
7530222 MGI
acts upstream of or within embryonic placenta morphogenesis IMP
IMP: Inferred from mutant phenotype
7530222 MGI
acts upstream of or within heart development IMP
IMP: Inferred from mutant phenotype
7539357 MGI
acts upstream of or within heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules IMP
IMP: Inferred from mutant phenotype
8145052 MGI
acts upstream of or within leukocyte cell-cell adhesion IMP
IMP: Inferred from mutant phenotype
8562500 MGI
Cellular Component GO Annotation Evidence References Source
located in apical plasma membrane IDA
IDA: Inferred from direct assay
30236446 MGI
located in cell periphery IDA
IDA: Inferred from direct assay
21464233 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

vascular cell adhesion protein 1

  • V-CAM 1

Recombinant Vcam1 Proteins

Cat. No. Product Name Accession Purity
HY-P72432 VCAM-1/CD106 Protein, Mouse (HEK293, Fc) P29533 (F25-E698) ≥ 95%, as determined by reducing SDS-PAGE.
HY-P73469 VCAM-1/CD106 Protein, Mouse (HEK293, His-Fc) Q3UPN1 (M1-E698) ≥ 90%, as determined by reducing SDS-PAGE.
HY-P73470 VCAM-1/CD106 Protein, Mouse (HEK293, His) Q3UPN1 (F25-E698) ≥ 95%, as determined by reducing SDS-PAGE or Bis-Tris PAGE.

Vcam1 Antibodies

Cat. No. Product Name Application Reactivity
HY-P810097 VCAM-1 Antibody (YA9441) WB, ICC/IF, IF-Tissue, FC, IP mouse, rat

Related Agents

  • Approval
  • Clinical Phase
  • Pre-clinical Phase

Approval

Bioactive MoleculesInhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-108831 Natalizumab Inhibitor 99.10% Unkown

Clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Phase
HY-167874 ASP-8731 Inhibitor 98.42% Phase 1
HY-136692 HMR 1031 Inhibitor / Phase 1

Pre-clinical Phase

Bioactive Molecules (29)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-112868B ABH hydrochloride 99.90% Unkown
HY-121705 Propionyl-L-carnitine 95.0% Unkown
HY-N0602 Ginsenoside Rg2 Inhibitor 98.71% Unkown
HY-N2110 Phellopterin 99.94% Unkown
HY-N1353 Rhamnocitrin Inhibitor 99.67% Unkown
HY-N0617 Sanggenon C 98.46% Unkown
HY-N7688 Regaloside B Inhibitor 99.90% Unkown
HY-139702 α5β1 integrin agonist-1 99.67% Unkown
HY-W588250 Surfactin C1 Antagonist 99.31% Unkown
HY-14921 Elsibucol Inhibitor 99.35% Unkown
HY-N0887 Isoastragaloside I 99.49% Unkown
HY-P11445 GREDVGC 99.45% Unkown
HY-P11088A VCAM1 binding peptide acetate Ligand 99.76% Unkown
HY-RS17114 Vcam1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-119142 CP-664511 Antagonist / Unkown
HY-143243 Antioxidant agent-5 Inhibitor / Unkown
HY-159179 α4 integrin receptor antagonist 3 Inhibitor / Unkown
HY-163712S 17-Epiestriol-d5-1 / Unkown
HY-170916 Angiogenesis inhibitor 7 Inhibitor / Unkown
HY-171216 GW559090 Antagonist / Unkown
HY-N0602R Ginsenoside Rg2 (Standard) Inhibitor / Unkown
HY-N10047 7,8-Didehydrocimigenol Inhibitor / Unkown
HY-P11088 VCAM1 binding peptide Ligand / Unkown
HY-P11887 VHPKQHR Ligand / Unkown
HY-RS15618 VCAM1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-112868A ABH Inhibitor / Unkown
HY-163712 17-Epiestriol Agonist / Unkown
HY-183448 ETMTC / Unkown
HY-RS23559 Vcam1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
Bioactive MoleculesInhibitory Antibodies (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-108831A Natalizumab (Anti-CD49d) Inhibitor 99.71% Unkown
HY-P990294 Anti-Mouse CD106/VCAM-1 Antibody (M/K-2.7) Inhibitor 95.00% Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Vcam1 NCBI NCBI:7412