2. Cytoskeleton
  3. Integrin
  4. GREDVGC

GREDVGC is a peptide. GREDVGC can mimic VCAM-1 for binding to integrin α4β1. GREDVGC can be used for the research of cancer.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

GREDVGC

GREDVGC Chemical Structure

CAS No. : 1810716-06-3

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GREDVGC Related Antibodies

Top Publications Citing Use of Products

View All Integrin Isoform Specific Products:

View All Isoforms
αvβ1 αvβ3 αvβ5 αvβ6 αvβ8 α5β1 α1β1 α2β1 α4β1 α9β1 αIIbβ3 α4β7 αLβ2

  • Biological Activity

  • Purity & Documentation

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Description

GREDVGC is a peptide. GREDVGC can mimic VCAM-1 for binding to integrin α4β1. GREDVGC can be used for the research of cancer[1].

IC50 & Target[1]

α4β1

 

Molecular Weight

734.78

Formula

C27H46N10O12S
CAS No.
Appearance

Solid

Color

White to light yellow

Sequence

Gly-Arg-Glu-Asp-Val-Gly-Cys
Sequence Shortening

GREDVGC
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : ≥ 100 mg/mL (136.10 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.3610 mL 6.8048 mL 13.6095 mL
5 mM 0.2722 mL 1.3610 mL 2.7219 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 1.3610 mL 6.8048 mL 13.6095 mL 34.0238 mL
5 mM 0.2722 mL 1.3610 mL 2.7219 mL 6.8048 mL
10 mM 0.1361 mL 0.6805 mL 1.3610 mL 3.4024 mL
15 mM 0.0907 mL 0.4537 mL 0.9073 mL 2.2683 mL
20 mM 0.0680 mL 0.3402 mL 0.6805 mL 1.7012 mL
25 mM 0.0544 mL 0.2722 mL 0.5444 mL 1.3610 mL
30 mM 0.0454 mL 0.2268 mL 0.4537 mL 1.1341 mL
40 mM 0.0340 mL 0.1701 mL 0.3402 mL 0.8506 mL
50 mM 0.0272 mL 0.1361 mL 0.2722 mL 0.6805 mL
60 mM 0.0227 mL 0.1134 mL 0.2268 mL 0.5671 mL
80 mM 0.0170 mL 0.0851 mL 0.1701 mL 0.4253 mL
100 mM 0.0136 mL 0.0680 mL 0.1361 mL 0.3402 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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GREDVGC Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

GREDVGC1810716-06-3IntegrinPeptideVCAM-1integrin α4β1Inhibitorinhibitorinhibit

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