MMP8 - matrix metallopeptidase 8 Gene

Also Known as HNC; CLG1; MMP-8; PMNL-CL

Species: Homo sapiens

Gene Type: protein coding

Gene ID: 4317

About MMP8

Cytogenetic location: 11q22.2 Genomic coordinates (GRCh38): 11:102,711,796-102,724,954 (from NCBI)

This gene has 6 transcripts (splice variants), 111 orthologues and 23 paralogues. Restricted expression toward bone marrow (RPKM 202.1).

Summary

This gene encodes a member of the matrix metalloproteinase (MMP) family of proteins. These proteins are involved in the breakdown of extracellular matrix in embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Proteolysis at different sites on this protein results in multiple active forms of the enzyme with distinct N-termini. This protein functions in the degradation of type I, II and III collagens. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]

MMP8 Products (7)

mRNA	Protein	Name
XM_011542835.3	XP_011541137.1	neutrophil collagenase isoform X2
NM_001304441.2	NP_001291370.1	neutrophil collagenase isoform 2
XM_011542834.3	XP_011541136.1	neutrophil collagenase isoform X1
NM_001304442.2	NP_001291371.1	neutrophil collagenase isoform 2
XM_047426966.1	XP_047282922.1	neutrophil collagenase isoform X3
NM_002424.3	NP_002415.1	neutrophil collagenase isoform 1 preproprotein
XM_047426965.1	XP_047282921.1	neutrophil collagenase isoform X2

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	References	Source
enables endopeptidase activity	IMP IMP: Inferred from mutant phenotype	25049354	GOA
enables peptidase activity	IDA IDA: Inferred from direct assay	23845380	GOA
enables serine-type endopeptidase activity	IDA IDA: Inferred from direct assay	2164002	GOA
enables tumor necrosis factor binding	IDA IDA: Inferred from direct assay	25049354	GOA

Biological Process GO Annotation	Evidence	References	Source
involved in endodermal cell differentiation	IEP IEP: Inferred from expression pattern	23154389	GOA
involved in positive regulation of tumor necrosis factor production	IMP IMP: Inferred from mutant phenotype	25049354	GOA
involved in proteolysis	IDA IDA: Inferred from direct assay	2164002	GOA

Cellular Component GO Annotation	Evidence	References	Source
located in extracellular space	IDA IDA: Inferred from direct assay	2164002	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

MMP8 Protein Structure

PG_binding_1

Peptidase_M10

Hemopexin

0
100
200
300
400
467 a.a.

Protein Preferred Names	Protein Names
neutrophil collagenase	PMN leukocyte collagenase PMNL collagenase collagenase 2 matrix metalloproteinase 8 (neutrophil collagenase) matrix metalloproteinase-8

Recombinant MMP8 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P72507	MMP-8 Protein, Human (HEK293, His)	P22894 (F21-G467)	≥ 90%, as determined by reducing SDS-PAGE.
HY-P73298	MMP-8 Protein, Human (HEK293)	P22894 (F21-G467)	≥ 90%, as determined by reducing SDS-PAGE.

MMP8 Antibodies

Cat. No.	Product Name	Application	Reactivity
HY-P83285	MMP8 Antibody (YA3030)	WB, IHC-P, ICC/IF, IP, FC	Human, Mouse, Rat

Related Diseases

Diseases	Alias
Preterm Premature Rupture Of The Membranes	Preterm Premature Rupture Of Membranes PPROM Preterm Premature Rupture Of The Membranes, Susceptibility To Pprom - [Preterm Premature Rupture Of Membranes] Preterm Rupture Of Membranes
Pulmonary Disease, Chronic Obstructive	Chronic Obstructive Pulmonary Disease COPD Pulmonary Disease, Chronic Obstructive, Severe Early-Onset Chronic Obstructive Lung Disease Chronic Obstructive Airway Disease Pulmonary Disease, Chronic Obstructive, Susceptibility To Cold Severe Early-Onset Chronic Obstructive Pulmonary Disease Pulmonary Disease Chronic Obstructive Pulmonary Disease, Obstructive, Chronic, Susceptibility To Chronic Obstructive Pulmonary Disease Of Horses Common Cold Upper Respiratory Infections Copd - [Chronic Obstructive Pulmonary Disease] Coad - [Chronic Obstructive Airways Disease] Cold - [Chronic Obstructive Lung Disease] Chronic Airway Disease Nos Chronic Airways Limitation, Unspecified Chronic Obstructed Airway, Unspecified Chronic Obstructive Airway Disease, Unspecified Chronic Obstructive Airway, Unspecified Obstructive Lung Disease Nos Chronic Obstructive Lung Disease Nos Chronic Obstructive Lung Nos Obstructive Pulmonary Disease Nos Exacerbation Copd Nos Acute Exacerbation Copd
Aortic Aneurysm, Familial Thoracic 1	Thoracic Aortic Aneurysm Annuloaortic Ectasia Familial Thoracic Aortic Aneurysm And Aortic Dissection Familial Aortic Dissection Familial Taad Congenital Aneurysm Of Ascending Aorta Familial Aortic Aneurysm Familial Thoracic Aortic Aneurysm Familial Thoracic Aortic Aneurysm And Dissection Aortic Aneurysm, Thoracic AAT1 Faa1 Aortic Dissection, Familial Aortic Aneurysm, Familial Thoracic Aneurysm, Thoracic Aortic Faa Ftaad Taa Taad Cystic Medial Necrosis Of Aorta Familial Non-Syndromic Thoracic Aortic Aneurysm And Aortic Dissection Aortic Aneurysm Thoracic Familial Aortic Aneurysms Aneurysm, Aortic, Thoracic, Familial, Type 1 Aneurysm Of Thoracic Aorta Intrathoracic Aneurysm Thoracic Aorta Aneurysm Thoracic Aortic Aneurysm Without Rupture Thoracic Aneurysm Thorax Arterial Aneurysm Thoracic Artery Aneurysm Thoracic Arterial Aneurysm Thorax Aneurysm Thorax Aortic Aneurysm Dissection Of Thoracic Aorta
Bronchiolitis Obliterans	Bronchiolitis Fibrosa Obliterans Obliterative Bronchiolitis Bronchiolitis Exudativa Bronchiolitis, Exudative
Rosacea	Erythematotelangiectatic Rosacea Papulopustular Rosacea Phymatous Rosacea Acne Roscea Acne, Erythematosa Granulomatous Rosacea Ocular Rosacea Acne Rosacea Hypertrophic Rosacea
Amaurosis Fugax	Transient Monocular Blindness Momentary Blindness Af - [Amaurosis Fugax] Transient Vision Loss, Spontaneous Amaurosis Fugax, Course Of Resolution Unspecified
Bacterial Meningitis	Meningitis, Bacterial Meningitis Bacterial Bm - [Bacterial Meningitis] Leptomeningitis Bacterial Pachymeningitis Bacterial Arachnoiditis Bacterial
Reactive Arthritis	Postdysenteric Arthropathy Reiter Disease Pira Reiter Syndrome Arthritis, Reactive Fiessinger Leroy Reiter Syndrome Post-Bacterial Arthropathy Reiter'S Disease Post-Infectious Arthritis Post-Infectious Reactive Arthropathy Reiter'S Syndrome Arthritis Urethritica Fiessinger-Leroy Disease Polyarthritis Enterica Venereal Arthritis Reiters Syndrome Arthritis Reactive Post-Dysenteric Arthropathy Arthritis, Venereal
Meningitis	Streptococcal Meningitis Acute Streptococcal Meningitis Staphylococcal Meningitis Adenoviral Meningitis Influenza Meningitis Influenzal Meningitis Meningitis Due To H. Influenzae Cryptococcal Meningitis Fungal Meningitis Due To Cryptococcus Neoformans Cryptococcosis Meningitis Cryptococcus Meningitis Cryptococcal Meningoencephalitis Meningitis Due To Cryptococcus Mumps Virus Meningitis Mumps Meningitis
Funisitis
Chorioamnionitis
Periodontitis, Aggressive, 1	Ppp Pustulosis Palmaris Et Plantaris Periodontitis, Juvenile Localized Pustular Psoriasis Jpd Periodontitis 1, Juvenile Lpp Palmoplantar Pustulosis Prepubertal Periodontitis Periodontitis, Aggressive 1 Periodontitis, Prepubertal Periodontititis, Aggressive, 1 AP1 Juvenile Periodontitis Periodontitis Juvenile Pustulosis Of Palms And Soles Generalized Pustular Psoriasis
Cystic Fibrosis	Mucoviscidosis CF Pseudomonas Aeruginosa, Susceptibility To Chronic Infection By, In Cystic Fibrosis Pseudomonas Aeruginosa Chronic Infection By, In Cystic Fibrosis Cystic Fibrosis Lung Disease, Modifier Of Cystic Fibrosis Of Pancreas Fibrocystic Disease Of Pancreas Cf - [Cystic Fibrosis] Cystic Fibrosis Nos Fibrocystic Disease Fibrocystic Disease Of The Pancreas Mucoviscidosis Of Pancreas Nonproliferative Fibrocystic Disease Pancreatic Cystic Fibrosis
Gingival Disease	Gingival Diseases Gum Disease Gingival Disorder Gingivitis And Periodontal Diseases
Cutis Laxa, Autosomal Dominant 2	ADCL2 Autosomal Dominant Cutis Laxa 2 Cutis Laxa, Autosomal Dominant, 2 Cutis Laxa, Autosomal Dominant, Type 2
Cutis Laxa, Autosomal Dominant 1	Cutis Laxa, Autosomal Dominant Autosomal Dominant Cutis Laxa ADCL1 Adcl Autosomal Dominant Cutis Laxa 1 Cutis Laxa, Autosomal Dominant, 1 Cutis Laxa, Autosomal Dominant, Type 1
Gastroschisis	Laparoschisis Congenital Fissure Of The Abdominal Cavity Abdominal Wall Defect Abdominal Hernia Hernia, Abdominal Omphalocele Abnormality Of The Abdominal Wall Congenital Omphalocele Coeloschisis Coelioschisis Celoschisis Congenital Para-Umbilical Hernia
Arthritis	Inflammatory Joint Disease Inflammatory Disorder Of Joint
Pelvic Organ Prolapse	Rectal Prolapse Pelvic Organ Prolapse, Susceptibility To Pelvic Organ Prolapse, Susceptibility To, 1 Prolapse Of Vagina And Rectum Vaginal Prolapse Pelvic Organ Prolapse 1 Procidentia, Rectum Prolapse Of Rectal Mucosa Procidentia Of Rectum Rectal Mucosa Prolapse Rectum Prolapse Procidentia Rectum Rp - [Rectal Prolapse] Male Proctocele Male Rectocele Proctoptosis Female Genital Prolapse Female Prolapse Incompetence Of Pelvic Fundus Relaxation Of Perineum Deficiency Of Perineum
Tendinopathy
Asthma	Chronic Obstructive Asthma Asthma, Diminished Response To Antileukotriene Treatment In Bronchial Hyperreactivity Asthma, Susceptibility To Asthma, Bronchial Asthma, Protection Against Asthma, Nocturnal, Susceptibility To Nocturnal Asthma Asthma-Related Traits Asthma-Related Traits, Susceptibility To Asthma, Nocturnal Chronic Obstructive Asthma With Acute Exacerbation Chronic Obstructive Asthma With Status Asthmaticus Exercise Induced Asthma Exercise-Induced Asthma Bronchial Asthma Asthma, Exercise-Induced Idiosyncratic Asthma Unspecified Asthma With Acute Exacerbation Asthma, Unspecified, With Stated Status Asthmaticus Status Asthmaticus Nos Acute Severe Asthma Acute Severe Bronchial Asthma Status Asthma Status Post Asthmaticus
Gingival Recession	Localized Gingival Recession Gingival Recession, Localized Minimal Gingival Recession Moderate Gingival Recession Severe Gingival Recession Gingival Recession, Minimal Gingival Recession, Severe Atrophy Of Gums Gum Atrophy Gingival Atrophy
Bronchiectasis	Polynesian Bronchiectasis Kartagener Syndrome Bronchiectasis Nos
Peritonitis	Retractile Mesenteritis Sclerosing Mesenteritis Acute Generalized Peritonitis Primary Bacterial Peritonitis Idiopathic Sclerosing Mesenteritis Mesenteric Panniculitis Peritoneal Retractile Mesenteritis Liposclerotic Mesenteritis Mesenteric Fibromatosis Mesenteric Lipodystrophy Mesenteric Lipogranuloma Fibromatosis, Abdominal Peritoneum Inflammation Peritonitis Of Undetermined Cause Peritonitis Of Unspecified Cause Pelviperitonitis Pelvic Peritonitis, Nos Generalised Peritonitis Nos Abdominal Peritonitis Acute Idiopathic Peritonitis Acute Lesser Sac Peritonitis Acute Peritoneal Inflammation Diffuse Peritonitis Peritoneal Inflammation Acute Primary Peritonitis Pneumococcal Peritonitis
Malaria	Malaria, Susceptibility To Malaria, Resistance To Malaria, Cerebral Cerebral Malaria Malaria, Severe, Susceptibility To Malaria, Severe, Resistance To Malaria, Cerebral, Susceptibility To Induced Malaria Malaria, Vivax, Protection Against Malaria, Severe Malaria, Cerebral, Reduced Risk Of Malaria, Protection Against Resistance To Malaria Due To G6pd Deficiency Malaria Due To G6pd Deficiency Malarial Encephalitis CM Malaria Cerebral Susceptibility To Malaria Acute Pernicious Fever Aestivo-Autumnal Fever Aestivo Autumnal Malaria Chagres Fever Continued Malaria Fever Estivo-Autumnal Fever Estivo-Autumnal Malaria Estivo-Autumnal Malarial Fever Falciparum Fever Malignant Tertian Fever Malignant Tertian Malaria Pernicious Intermittent Fever Pernicious Malaria Quotidian Malaria Subtertian Fever Subtertian Malaria Fever Subtertian Malignant Tertian Malaria Tropical Malaria Algid Malaria Bilious Haemoglobinuric Fever Black Water Fever Blackwater Fever Malarial Blackwater Fever Severe Malarial Falciparum West African Fever Malarial Haematinuria Haemoglobinuric Fever Haemoglobinuric Malaria Severe Plasmodium Falciparum Malaria Malarial Haemoglobinuria Malarial Haematuria Falciparum Malaria [Malignant Tertian] Malaria Tropica Malarial Shock Chagres Virus Disease Malignant Malaria Mtm - [Malignant Tertian Malaria] Tm -[Malignant Tertian Malaria] Panama Fever St - [Subtertian Malaria] Malarial Quotidian Benign Tertian Malaria Tertian Ague Vivax Fever Plasmodium Vivax Malaria Nos Btm - [Benign Tertian Malaria] Bt - [Benign Tertian Malaria] Vivax Malaria Benign Tertian Vivax Malaria Tertian Malaria Quartan Malaria Quartan Ague Quartan Fever Plasmodium Malariae Malaria Nos Quartan Malarial Malaria By Plasmodium Malariae Malariae Malaria Ovale Tertian Malaria Plasmodium Ovale Fever Malaria Fever By Plasmodium Ovale Ovale Malaria Malaria By Plasmodium Ovale Malarial Ovale Marsh Fever Remittent Congestive Fever Coastal Fever Remittent Gastric Fever Miasmatic Fever Congestive Remittent Fever Intermittent Fever Jungle Fever Paludism Cameroon Fever Ague Corsican Fever Intermittent Bilious Fever Disease Due To Plasmodiidae Malarial Fever Plasmodiosis Remittent Fever Roman Fever Malaria Fever Nos Malaria Nos Paludal Fever Clinically Diagnosed Malaria Clinically Diagnosed Malaria Without Parasitological Confirmation Congestive Fever Malarial Cachexia Marsh Cachexia Paludal Cachexia Recurrent Malaria Remittent Malaria
Immune Deficiency Disease	Immunodeficiency Primary Immunodeficiency Disease Primary Immunodeficiency Immunologic Deficiency Syndromes Hypoimmunity Immune Deficiency Disorder Immunodeficiency Syndrome Immune Disorder Primary Immune Deficiency Disorder Immune System Diseases Human Immunodeficiency Virus Infection Hiv - [Human Immunodeficiency Virus Infection] Hiv Positive Nos Hiv Disease Acquired Immune Deficiency Syndrome-Related Complex Aids-Like Syndrome Aids-Related Complex Nos Arc - [Aids-Related Complex] Immunodeficiency Due To Human Immunodeficiency Virus Infection Unspecified Human Immunodeficiency Virus Disease Hiv Disease Nos Human Immunodeficiency Virus Positive Nos Hiv Nos Deficiency Of Complement Initial Pathway Deficiency Of Complement Terminal Pathway Cfdd - [Complement Factor D Deficiency] Immunodeficiency With Nk-Cell - [Natural-Killer Cell] Deficiency Nonfamilial Hypogammaglobulinaemia Common Variable Immune Deficiency Nonfamilial Agammaglobulinaemia Common Variable Agammaglobulinaemia Agammaglobulinaemia Nos Agammaglobulinaemia Antibody Deficiency Syndrome Hypogammaglobulinaemia Antibody Deficiency Syndrome Acquired Agammaglobulinaemia Nos Hypogammaglobulinaemia Nos Hyper Igm
Malignant Ovarian Cyst
Periapical Granuloma	Apical Granuloma
Epidermolysis Bullosa Acquisita	Acquired Epidermolysis Bullosa Eb Acquisita Eba Eba - [Epidermolysis Bullosa Acquisita]
Chronic Ulcer Of Skin	Chronic Wounds Callous Ulcer Indolent Ulcer Chronic Ulcer
Aggressive Periodontitis	Juvenile Periodontitis Periodontitis, Juvenile Prepubertal Periodontitis
Periapical Periodontitis	Apical Periodontitis Periodontitis Apical
Gingivitis	Chronic Gingivitis Acute Gingivitis
Osteoporosis	Postmenopausal Osteoporosis Osteoporosis, Postmenopausal Bone Mineral Density Quantitative Trait Locus Bmnd Osteoporosis, Involutional Osteoporosis, Susceptibility To Osteoporosis, Postmenopausal, Susceptibility Bone Mineral Density Variation Qtl, Osteoporosis OSTEOP Involutional Osteoporosis Senile Osteoporosis Osteoporosis Postmenopausal Bone Mineral Density, Quantitative Trait Locus Osteoporosis, Senile Idiopathic Osteoporosis Bone Rarefaction Nos Type 1 Osteoporosis
Aortic Aneurysm	Aortic Rupture Thoracoabdominal Aortic Aneurysm, Ruptured Ruptured Aortic Aneurysm Aortic Aneurysms Aortic Aneurysm Without Mention Of Rupture Nos Ruptured Abdominal Aortic Aneurysm Aortic Aneurysm, Ruptured Ruptured Thoracic Aortic Aneurysm
Chronic Apical Periodontitis	Apical Periodontitis Nos Apex Periodontitis Periapical Infection Nos
Acute Pericementitis	Acute Periodontitis Aggressive And Acute Periodontitis Peridental Infection Periodontal Infection
Dentin Caries	Compound Dental Caries Dental Caries Extending Into Dentine Dental Caries Extending Into Dentin
Aortic Aneurysm, Familial Abdominal, 1	Abdominal Aortic Aneurysm Aortic Aneurysm, Familial Abdominal 1 Aneurysm, Abdominal Aortic AAA Aortic Aneurysm, Abdominal AAA1 Aortic Aneurysm, Familial Abdominal Aortic Aneurysm Abdominal Abdominal Aortic Aneurysms Abdominal Aortic Aneurysm Without Mention Of Perforation Or Rupture Abdomen Aneurysm Abdominal Aorta Aneurysm Aneurysm Of Abdominal Aorta Aortic Abdomen Aneurysm Aaa - [Abdominal Aortic Aneurysm] Abdominal Aneurysm Abdominal Aorta Aneurysm Rupture Abdominal Aorta Aneurysm Ruptured Abdominal Aortic Aneurysm Which Has Ruptured Ruptured Aaa Abdomen Aorta Aneurysm Ruptured Abdomen Aorta Rupture Abdomen Aortic Aneurysm Rupture Abdomen Aneurysm Rupture Abdomen Aortic Aneurysm Ruptured Abdomen Aortic Rupture Abdominal Aorta Rupture Abdominal Aortic Rupture Rupture Abdomen Aorta Aneurysm Rupture Abdominal Aortic Aneurysm Ruptured Abdomen Aneurysm Ruptured Abdomen Aorta Ruptured Abdomen Aortic Ruptured Abdominal Aneurysm Ruptured Abdominal Aorta Ruptured Abdominal Aortic Ruptured Aorta Abdominalis Aneurysm False Abdomen Aorta Aneurysm Ruptured False Abdominal Aortic Aneurysm Ruptured False Abdominal Aorta Aneurysm Ruptured False Abdomen Aortic Aneurysm Ruptured
Gingival Overgrowth	Gingival Enlargement Gingival Hyperplasia Gingival Bulge Gingival Enlargement Nos Gingival Hypertrophy Gum Hypertrophy Hyperplasia Gum Gingival Thickening Hyperplasia Of Gingiva Hypertrophy Of Gingiva Hypertrophy Of Mucous Membrane Of Gums
Periodontitis	Chronic Pericementitis Chronic Periodontitis
Cutis Laxa, Autosomal Dominant 3	ADCL3 Autosomal Dominant Cutis Laxa 3 Cutis Laxa, Autosomal Dominant, 3
Periodontitis, Chronic	Chronic Periodontitis Periodontitis, Adult
Pulmonary Emphysema
Root Caries	Cementum Caries Dental Caries Of Root Surface
Cerebral Palsy	Infantile Cerebral Palsy Mixed Cerebral Palsy Palsy Cerebral Palsy, Cerebral Cerebral Palsy, Mixed
Lipoprotein Quantitative Trait Locus	Coronary Artery Disease Coronary Artery Disease, Susceptibility To Coronary Artery Anomaly Myocardial Ischemia Congenital Anomaly Of Coronary Artery Coronary Arteriosclerosis Coronary Disease Coronary Heart Disease Coronary Artery Disorder LPAQTL Lpa Deficiency, Congenital Coronary Artery Abnormality Coronary Artery Anomaly, Congenital Chd Coronary Syndrome Congenital Malformations Of Coronary Vessels Malformation Of Coronary Vessels Congenital Coronary Artery Anomaly Congenital Coronary Artery Deformity Congenital Coronary Artery Disorder Abnormal Coronary Artery Congenital Coronary Artery Malposition Congenital Coronary Disease Congenital Anomaly Of Coronary Arteries
Rheumatoid Arthritis	RA Arthritis, Rheumatoid Rheumatoid Arthritis, Susceptibility To Arthritis Or Polyarthritis, Rheumatic Atrophic Arthritis Rheumatism Arthritis Rheumatoid Polyarthritis
Synovitis
Blepharoconjunctivitis
Tongue Carcinoma	Tongue Cancer Malignant Neoplasm Of Tongue Tongue Neoplasms Tongue Neoplasm
Interstitial Lung Disease 2	Idiopathic Pulmonary Fibrosis Ipf Fibrocystic Pulmonary Dysplasia Pulmonary Fibrosis, Idiopathic Pulmonary Fibrosis, Idiopathic, Susceptibility To ILD2 Idiopathic Pulmonary Fibrosis, Familial Fibrosing Alveolitis, Cryptogenic Uip Cryptogenic Fibrosing Alveolitis Fibrosing Alveolitis Interstitial Pneumonitis, Usual Familial Idiopathic Pulmonary Fibrosis Idiopathic Fibrosing Alveolitis, Chronic Form Usual Interstitial Pneumonia Fibrosing Alveolitis Cryptogenic Hamman-Rich Disease Idiopathic Pulmonary Fibrosis Familial Interstitial Pneumonitis Usual Fibrosis Idiopathic Pulmonary Fibrosis, Pulmonary, Idiopathic Hamman-Rich Syndrome Chronic Idiopathic Pulmonary Fibrosis Acute Interstitial Pneumonia Interstitial Pulmonary Fibrosis Ipf - [Idiopathic Pulmonary Fibrosis] Idiopathic Lung Fibrosis Fibrosing Lung Disease Pulmonary Fibrosis Nos Fibrosing Pneumonitis

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Clinical Phase
Pre-clinical Phase

Clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Phase
HY-112160	XL-784 free base	Inhibitor	/	Phase 2

Pre-clinical Phase

Bioactive Molecules (32)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-148905	p-Aminophenylmercuric acetate	Activator	98.32%	Unkown
HY-110397	KP-457	Inhibitor	99.18%	Unkown
HY-113952	Actinonin		98.37%	Unkown
HY-P4931	Mca-KPLGL-Dap(Dnp)-AR-NH2		99.30%	Unkown
HY-N1454	Apigenin-7-glucuronide	Inhibitor	99.74%	Unkown
HY-128133	MMP-8 inhibitor-1	Inhibitor	99.70%	Unkown
HY-N1463	Luteolin 7-O-glucuronide	Inhibitor	99.98%	Unkown
HY-162038	RXP03	Inhibitor	98.82%	Unkown
HY-107639	UK-370106	Inhibitor	≥99.0%	Unkown
HY-110397G	KP-457 (GMP)	Inhibitor	/	Unkown
HY-19485	XL-784	Inhibitor	98.25%	Unkown
HY-114091	PF-00356231 hydrochloride	Inhibitor	99.52%	Unkown
HY-147745	MMP2-IN-2	Inhibitor	98.80%	Unkown
HY-110116	SD-2590 hydrochloride	Inhibitor	99.4%	Unkown
HY-147746	MMP2-IN-3	Inhibitor	99.64%	Unkown
HY-RS08555	Mmp8 Mouse Pre-designed siRNA Set A		/	Unkown
HY-113621B	Ageladine A dihydrochloride	Inhibitor	/	Unkown
HY-114091A	PF-00356231	Inhibitor	/	Unkown
HY-114396	BR351	Inhibitor	/	Unkown
HY-137793	Pro-Leu-Gly-NHOH hydrochloride	Inhibitor	/	Unkown
HY-168605	DH-18		/	Unkown
HY-175275	10-Butyl Ether Minocycline	Inhibitor	/	Unkown
HY-180765	Colchicine-O-CO-Enyl(Me)-Enyl-Enyl(Me)-Enyl-1,3,3-trimethylcyclohex-1-ene	Activator	/	Unkown
HY-182795	Colchicine derivative-1		/	Unkown
HY-P10972	GIP (22-51) human		/	Unkown
HY-P2682	MMP-8/MMP-26 Fluorogenic substrate		/	Unkown
HY-P3699	TNO003	Substrate	/	Unkown
HY-RS08554	MMP8 Human Pre-designed siRNA Set A		/	Unkown
HY-RS08556	Mmp8 Rat Pre-designed siRNA Set A		/	Unkown
HY-35513	3-Aminobenzene-1,2-diol	Inhibitor	98.0%	Unkown
HY-43586	BR351 precursor	Inhibitor	/	Unkown
HY-P3699A	TNO003 TFA	Substrate	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	MMP8	MGD	MGI:1202395
Felis catus	MMP8	VGNC	VGNC:68291
Rattus norvegicus	MMP8	RGD	RGD:631408
Canis familiaris	MMP8	VGNC	VGNC:43289
Macaca mulatta	MMP8	VGNC	VGNC:74902
Bos taurus	MMP8	VGNC	VGNC:31530
Others	MMP8	NCBI