SD-2590 hydrochloride
Based on 1 Customer Validation
SD-2590 hydrochloride is a potent MMP inhibitor with IC50 values of ﹤0.1, ﹤0.1, 0.18, and 1.7 nM for MMP2, MMP13, MMP9, and MMP8, respectively. SD-2590 hydrochloride inhibits dilation of the left ventricle in rats.
For research use only. We do not sell to patients.
- Purity: 99.4%
- CAS No.: 226395-93-3
- Formula: C22H26ClF3N2O7S
- Molecular Weight:554.96
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Storage:
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Biological Activity
Chemical Information
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CAS No. 226395-93-3
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Appearance Solid
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Molecular Weight 554.96
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Formula C22H26ClF3N2O7S
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Color White to off-white
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SMILES
O=S(C1(CCN(CCOC)CC1)C(NO)=O)(C2=CC=C(OC3=CC=C(OC(F)(F)F)C=C3)C=C2)=O.Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
DMSO : 55.5 mg/mL (100.01 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (268 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.8019 mL | 9.0097 mL | 18.0193 mL | 45.0483 mL |
| 5 mM | 0.3604 mL | 1.8019 mL | 3.6039 mL | 9.0097 mL | |
| 10 mM | 0.1802 mL | 0.9010 mL | 1.8019 mL | 4.5048 mL | |
| 15 mM | 0.1201 mL | 0.6006 mL | 1.2013 mL | 3.0032 mL | |
| 20 mM | 0.0901 mL | 0.4505 mL | 0.9010 mL | 2.2524 mL | |
| 25 mM | 0.0721 mL | 0.3604 mL | 0.7208 mL | 1.8019 mL | |
| 30 mM | 0.0601 mL | 0.3003 mL | 0.6006 mL | 1.5016 mL | |
| 40 mM | 0.0450 mL | 0.2252 mL | 0.4505 mL | 1.1262 mL | |
| 50 mM | 0.0360 mL | 0.1802 mL | 0.3604 mL | 0.9010 mL | |
| 60 mM | 0.0300 mL | 0.1502 mL | 0.3003 mL | 0.7508 mL | |
| 80 mM | 0.0225 mL | 0.1126 mL | 0.2252 mL | 0.5631 mL | |
| 100 mM | 0.0180 mL | 0.0901 mL | 0.1802 mL | 0.4505 mL |