2. Gene
  3. IMPACT - impact RWD domain protein Gene

IMPACT - impact RWD domain protein Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as RWDD5

Gene ID: 55364 | Gene type: protein coding

About IMPACT

Cytogenetic location: 18q11.2 Genomic coordinates (GRCh38): 18:24,426,670-24,453,531 (from NCBI)

This gene has 7 transcripts (splice variants) and 209 orthologues. Ubiquitous expression in thyroid (RPKM 17.1), testis (RPKM 17.0) and 25 other tissues.

Summary

Predicted to enable actin binding activity and ribosome binding activity. Predicted to be involved in several processes, including GCN2-mediated signaling; cellular response to starvation; and negative regulation of nitrogen compound metabolic process. Predicted to be located in cytoplasm. Predicted to be part of polysome. [provided by Alliance of Genome Resources, Apr 2022]

IMPACT Products(1)

mRNA Protein Name
NM_018439.4 NP_060909.2 protein IMPACT

IMPACT Protein Structure

RWD

RWD: RWD domain (8 - 112)

UPF0029

UPF0029: Uncharacterized protein family UPF0029 (181 - 289)

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  • 320 a.a.
Protein Preferred Names Protein Names

protein IMPACT

Impact homolog

Related Agents

Clinical Phase
Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Phase
HY-P99359 Elezanumab Inhibitor 99.69% Phase 2
Pre-clinical Phase
Bioactive Molecules (20)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-B0990 Thiostrepton Inhibitor 99.80% Unkown
HY-N0123 Aloin Inhibitor 98.32% Unkown
HY-114395 NVS-ZP7-4 Inhibitor 98.58% Unkown
HY-W034953 Bathocuproine disulfonate disodium 99.53% Unkown
HY-136528 RA-9 98.67% Unkown
HY-131697 FeTPPS Inhibitor ≥95.0% Unkown
HY-114395A (R)-NVS-ZP7-4 99.00% Unkown
HY-N2500 Deoxypodophyllotoxin 99.87% Unkown
HY-143226 DK1 Modulator 99.69% Unkown
HY-B0439S1 Sulfadoxine D3 Inhibitor ≥98.0% Unkown
HY-P5307 Peptide A5K / Unkown
HY-148384 UHMCP1 Inhibitor / Unkown
HY-148384A UHMCP1 dihydrochloride Inhibitor / Unkown
HY-152095 PPI-GIT1/β-Pix interaction-IN-1 Inhibitor / Unkown
HY-155237 LIN28-IN-1 Inhibitor / Unkown
HY-156283 Antibacterial agent 159 / Unkown
HY-160685 GW809897X Inhibitor / Unkown
HY-RS06797 IMPACT Human Pre-designed siRNA Set A / Unkown
HY-W250147 Basic blue 26 / Unkown
HY-109006 Ilmetropium iodide Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus IMPACT VGNC VGNC:62918
Canis familiaris IMPACT VGNC VGNC:42008
Mus musculus IMPACT MGD MGI:1098233
Rattus norvegicus IMPACT RGD RGD:1591977
Bos taurus IMPACT VGNC VGNC:30186