C2CD2L - C2CD2 like Gene
Also Known as DLNB23; TMEM24
Species: Homo sapiens
Gene Type: protein coding
Gene ID: 9854
Summary
Enables phosphatidylinositol binding activity and phosphatidylinositol transfer activity. Involved in positive regulation of Insulin secretion involved in cellular response to glucose stimulus. Located in cortical endoplasmic reticulum; cytoplasmic side of apical plasma membrane; and endoplasmic reticulum-plasma membrane contact site. [provided by Alliance of Genome Resources, Jul 2025]
Ubiquitous expression in brain (RPKM 6.4), small intestine (RPKM 5.5) and 25 other tissues.
C2CD2L Products (5)
| mRNA | Protein | Name |
|---|---|---|
| NM_001290474.2 | NP_001277403.1 | phospholipid transfer protein C2CD2L isoform 2 |
| NM_001382611.1 | NP_001369540.1 | phospholipid transfer protein C2CD2L isoform 3 |
| NM_001382612.1 | NP_001369541.1 | phospholipid transfer protein C2CD2L isoform 4 |
| NM_001382613.1 | NP_001369542.1 | phospholipid transfer protein C2CD2L isoform 2 |
| NM_014807.5 | NP_055622.3 | phospholipid transfer protein C2CD2L isoform 1 |
| Molecular Function GO Annotation | Evidence | References | Source |
|---|---|---|---|
| enables phosphatidylinositol binding |
IDA
IDA: Inferred from direct assay
|
28209843 | GOA |
| enables phosphatidylinositol transfer activity |
IDA
IDA: Inferred from direct assay
|
28209843 | GOA |
| enables protein binding |
IPI
IPI: Inferred from physical interaction
|
32296183 | GOA |
| Biological Process GO Annotation | Evidence | References | Source |
|---|---|---|---|
| involved in positive regulation of insulin secretion involved in cellular response to glucose stimulus |
IMP
IMP: Inferred from mutant phenotype
|
28209843 | GOA |
| Cellular Component GO Annotation | Evidence | References | Source |
|---|---|---|---|
| located in cortical endoplasmic reticulum |
IDA
IDA: Inferred from direct assay
|
28209843 | GOA |
| colocalizes with cytoplasmic side of apical plasma membrane |
IDA
IDA: Inferred from direct assay
|
28209843 | GOA |
| located in endoplasmic reticulum-plasma membrane contact site |
IDA
IDA: Inferred from direct assay
|
28209843 | GOA |
EXP: Inferred from Experiment
IDA: Inferred from direct assay
IPI: Inferred from physical interaction
IMP: Inferred from mutant phenotype
IGI: Inferred from genetic interaction
IEP: Inferred from expression pattern
Compound Screening Libraries
Virtual Screening
Customize Your Library
Drug Screening Service
C2CD2L Protein-protein interaction Information
|
Type
|
Protein Name | Protein ID | Interactor | Interactor Species | Interactor ID | Detection Method | References |
|---|---|---|---|---|---|---|---|
|
Intra
|
C2CD2L | O14523 | TMEM248 | Homo sapiens | Q9NWD8 | 32296183 | |
|
Intra
|
C2CD2L | O14523 | TMEM248 | Homo sapiens | Q9NWD8 | 32296183 | |
|
Intra
|
C2CD2L | O14523 | TMEM248 | Homo sapiens | Q9NWD8 | 32296183 | |
|
Intra
|
C2CD2L | O14523 | CISD2 | Homo sapiens | Q8N5K1 | 32296183 | |
|
Intra
|
C2CD2L | O14523 | CISD2 | Homo sapiens | Q8N5K1 | 32296183 | |
|
Intra
|
C2CD2L | O14523 | CISD2 | Homo sapiens | Q8N5K1 | 32296183 | |
|
Intra
|
C2CD2L | O14523 | ELOVL5 | Homo sapiens | Q9NYP7 | 32296183 | |
|
Intra
|
C2CD2L | O14523 | ELOVL5 | Homo sapiens | Q9NYP7 | 32296183 | |
|
Intra
|
C2CD2L | O14523 | ELOVL5 | Homo sapiens | Q9NYP7 | 32296183 | |
|
Intra
|
C2CD2L | O14523 | REEP2 | Homo sapiens | Q9BRK0 | 32296183 | |
|
Intra
|
C2CD2L | O14523 | REEP2 | Homo sapiens | Q9BRK0 | 32296183 | |
|
Intra
|
C2CD2L | O14523 | REEP2 | Homo sapiens | Q9BRK0 | 32296183 | |
|
Intra
|
C2CD2L | O14523 | ARL13B | Homo sapiens | Q3SXY8 | 32296183 | |
|
Intra
|
C2CD2L | O14523 | ARL13B | Homo sapiens | Q3SXY8 | 32296183 | |
|
Intra
|
C2CD2L | O14523 | ARL13B | Homo sapiens | Q3SXY8 | 32296183 | |
|
Intra
|
C2CD2L | O14523 | HIBADH | Homo sapiens | P31937 | 32296183 | |
|
Intra
|
C2CD2L | O14523 | HIBADH | Homo sapiens | P31937 | 32296183 | |
|
Intra
|
C2CD2L | O14523 | HIBADH | Homo sapiens | P31937 | 32296183 | |
|
Intra
|
C2CD2L | O14523 | TMEM179B | Homo sapiens | Q7Z7N9 | 32296183 | |
|
Intra
|
C2CD2L | O14523 | TMEM179B | Homo sapiens | Q7Z7N9 | 32296183 | |
|
Intra
|
C2CD2L | O14523 | TMEM179B | Homo sapiens | Q7Z7N9 | 32296183 | |
|
Intra
|
C2CD2L | O14523 | TMPRSS2 | Homo sapiens | O15393-2 | 32296183 | |
|
Intra
|
C2CD2L | O14523 | TMPRSS2 | Homo sapiens | O15393-2 | 32296183 | |
|
Intra
|
C2CD2L | O14523 | TMPRSS2 | Homo sapiens | O15393-2 | 32296183 | |
|
Intra
|
C2CD2L | O14523 | OPRM1 | Homo sapiens | P35372-10 | 32296183 | |
|
Intra
|
C2CD2L | O14523 | OPRM1 | Homo sapiens | P35372-10 | 32296183 | |
|
Intra
|
C2CD2L | O14523 | OPRM1 | Homo sapiens | P35372-10 | 32296183 | |
|
Intra
|
C2CD2L | O14523 | CXCR3 | Homo sapiens | P49682 | 32296183 | |
|
Intra
|
C2CD2L | O14523 | CXCR3 | Homo sapiens | P49682 | 32296183 | |
|
Intra
|
C2CD2L | O14523 | CXCR3 | Homo sapiens | P49682 | 32296183 | |
|
Intra
|
C2CD2L | O14523 | ZDHHC15 | Homo sapiens | Q96MV8 | 32296183 | |
|
Intra
|
C2CD2L | O14523 | ZDHHC15 | Homo sapiens | Q96MV8 | 32296183 | |
|
Intra
|
C2CD2L | O14523 | ZDHHC15 | Homo sapiens | Q96MV8 | 32296183 | |
|
Intra
|
C2CD2L | O14523 | AQP6 | Homo sapiens | Q13520 | 32296183 | |
|
Intra
|
C2CD2L | O14523 | AQP6 | Homo sapiens | Q13520 | 32296183 | |
|
Intra
|
C2CD2L | O14523 | AQP6 | Homo sapiens | Q13520 | 32296183 | |
|
Intra
|
C2CD2L | O14523 | TMEM88 | Homo sapiens | Q6PEY1 | 32296183 | |
|
Intra
|
C2CD2L | O14523 | TMEM88 | Homo sapiens | Q6PEY1 | 32296183 | |
|
Intra
|
C2CD2L | O14523 | TMEM88 | Homo sapiens | Q6PEY1 | 32296183 | |
|
Intra
|
C2CD2L | O14523 | MUC1 | Homo sapiens | P15941-11 | 32296183 | |
|
Intra
|
C2CD2L | O14523 | MUC1 | Homo sapiens | P15941-11 | 32296183 | |
|
Intra
|
C2CD2L | O14523 | MUC1 | Homo sapiens | P15941-11 | 32296183 | |
|
Intra
|
C2CD2L | O14523 | CLRN1 | Homo sapiens | P58418 | 32296183 | |
|
Intra
|
C2CD2L | O14523 | CLRN1 | Homo sapiens | P58418 | 32296183 | |
|
Intra
|
C2CD2L | O14523 | CHODL | Homo sapiens | Q9H9P2 | 32296183 | |
|
Intra
|
C2CD2L | O14523 | CHODL | Homo sapiens | Q9H9P2 | 32296183 | |
|
Intra
|
C2CD2L | O14523 | CHODL | Homo sapiens | Q9H9P2 | 32296183 | |
|
Intra
|
C2CD2L | O14523 | GJA8 | Homo sapiens | P48165 | 32296183 | |
|
Intra
|
C2CD2L | O14523 | GJA8 | Homo sapiens | P48165 | 32296183 | |
|
Intra
|
C2CD2L | O14523 | GJA8 | Homo sapiens | P48165 | 32296183 | |
|
Intra
|
C2CD2L | O14523 | GJB1 | Homo sapiens | P08034 | 32296183 | |
|
Intra
|
C2CD2L | O14523 | GJB1 | Homo sapiens | P08034 | 32296183 | |
|
Intra
|
C2CD2L | O14523 | GJB1 | Homo sapiens | P08034 | 32296183 | |
|
Intra
|
C2CD2L | O14523 | IL3RA | Homo sapiens | P26951 | 32296183 | |
|
Intra
|
C2CD2L | O14523 | IL3RA | Homo sapiens | P26951 | 32296183 | |
|
Intra
|
C2CD2L | O14523 | IL3RA | Homo sapiens | P26951 | 32296183 | |
|
Intra
|
C2CD2L | O14523 | SLC18A1 | Homo sapiens | P54219-3 | 32296183 | |
|
Intra
|
C2CD2L | O14523 | SLC18A1 | Homo sapiens | P54219-3 | 32296183 | |
|
Intra
|
C2CD2L | O14523 | SLC18A1 | Homo sapiens | P54219-3 | 32296183 | |
|
Intra
|
C2CD2L | O14523 | SLC10A6 | Homo sapiens | Q3KNW5 | 32296183 | |
|
Intra
|
C2CD2L | O14523 | SLC10A6 | Homo sapiens | Q3KNW5 | 32296183 | |
|
Intra
|
C2CD2L | O14523 | SLC10A6 | Homo sapiens | Q3KNW5 | 32296183 | |
|
Intra
|
C2CD2L | O14523 | AMIGO1 | Homo sapiens | Q86WK6 | 32296183 | |
|
Intra
|
C2CD2L | O14523 | AMIGO1 | Homo sapiens | Q86WK6 | 32296183 | |
|
Intra
|
C2CD2L | O14523 | AMIGO1 | Homo sapiens | Q86WK6 | 32296183 | |
|
Intra
|
C2CD2L | O14523 | TMEM86B | Homo sapiens | Q8N661 | 32296183 | |
|
Intra
|
C2CD2L | O14523 | TMEM86B | Homo sapiens | Q8N661 | 32296183 | |
|
Intra
|
C2CD2L | O14523 | TMEM86B | Homo sapiens | Q8N661 | 32296183 | |
|
Intra
|
C2CD2L | O14523 | EBP | Homo sapiens | Q15125 | 32296183 | |
|
Intra
|
C2CD2L | O14523 | EBP | Homo sapiens | Q15125 | 32296183 | |
|
Intra
|
C2CD2L | O14523 | EBP | Homo sapiens | Q15125 | 32296183 | |
|
Intra
|
C2CD2L | O14523 | MFSD5 | Homo sapiens | Q6N075 | 32296183 | |
|
Intra
|
C2CD2L | O14523 | MFSD5 | Homo sapiens | Q6N075 | 32296183 | |
|
Intra
|
C2CD2L | O14523 | MFSD5 | Homo sapiens | Q6N075 | 32296183 | |
|
Intra
|
C2CD2L | O14523 | TMX2 | Homo sapiens | Q9Y320 | 32296183 | |
|
Intra
|
C2CD2L | O14523 | TMX2 | Homo sapiens | Q9Y320 | 32296183 | |
|
Intra
|
C2CD2L | O14523 | TMX2 | Homo sapiens | Q9Y320 | 32296183 | |
|
Intra
|
C2CD2L | O14523 | BIK | Homo sapiens | Q13323 | 32296183 | |
|
Intra
|
C2CD2L | O14523 | BIK | Homo sapiens | Q13323 | 32296183 | |
|
Intra
|
C2CD2L | O14523 | BIK | Homo sapiens | Q13323 | 32296183 | |
|
Intra
|
C2CD2L | O14523 | PDZK1IP1 | Homo sapiens | Q13113 | 32296183 | |
|
Intra
|
C2CD2L | O14523 | PDZK1IP1 | Homo sapiens | Q13113 | 32296183 | |
|
Intra
|
C2CD2L | O14523 | PDZK1IP1 | Homo sapiens | Q13113 | 32296183 | |
|
Intra
|
C2CD2L | O14523 | TMEM9 | Homo sapiens | Q9P0T7 | 32296183 | |
|
Intra
|
C2CD2L | O14523 | TMEM9 | Homo sapiens | Q9P0T7 | 32296183 | |
|
Intra
|
C2CD2L | O14523 | TMEM9 | Homo sapiens | Q9P0T7 | 32296183 | |
|
Intra
|
C2CD2L | O14523 | LEPROTL1 | Homo sapiens | O95214 | 32296183 | |
|
Intra
|
C2CD2L | O14523 | LEPROTL1 | Homo sapiens | O95214 | 32296183 | |
|
Intra
|
C2CD2L | O14523 | LEPROTL1 | Homo sapiens | O95214 | 32296183 | |
|
Intra
|
C2CD2L | O14523 | REEP4 | Homo sapiens | Q9H6H4 | 32296183 | |
|
Intra
|
C2CD2L | O14523 | REEP4 | Homo sapiens | Q9H6H4 | 32296183 | |
|
Intra
|
C2CD2L | O14523 | REEP4 | Homo sapiens | Q9H6H4 | 32296183 | |
|
Intra
|
C2CD2L | O14523 | CD79A | Homo sapiens | P11912 | 32296183 | |
|
Intra
|
C2CD2L | O14523 | CD79A | Homo sapiens | P11912 | 32296183 | |
|
Intra
|
C2CD2L | O14523 | CD79A | Homo sapiens | P11912 | 32296183 | |
|
Intra
|
C2CD2L | O14523 | ERGIC3 | Homo sapiens | Q9Y282 | 32296183 | |
|
Intra
|
C2CD2L | O14523 | ERGIC3 | Homo sapiens | Q9Y282 | 32296183 | |
|
Intra
|
C2CD2L | O14523 | ERGIC3 | Homo sapiens | Q9Y282 | 32296183 | |
|
Intra
|
C2CD2L | O14523 | TMEM14B | Homo sapiens | Q9NUH8 | 32296183 | |
|
Intra
|
C2CD2L | O14523 | TMEM14B | Homo sapiens | Q9NUH8 | 32296183 | |
|
Intra
|
C2CD2L | O14523 | TMEM14B | Homo sapiens | Q9NUH8 | 32296183 |
Cross: Cross-species interaction
Intra: Intraspecies interaction