GSK-3β/HDAC-IN-1
GSK-3β/HDAC-IN-1 (Compd 4) is a brain-penetrant and first in class dual non-ATP-competitive Glycogen Synthase Kinase 3β/Histone Deacetylases (GSK-3β/HDACs) Inhibitor with IC50s of 0.142, 0.03 and 0.045 μM against GSK-3β, HDAC2 and HDAC6, respectively. GSK-3β/HDAC-IN-1 can be used for Alzheimer’s disease research.
For research use only. We do not sell to patients.
- Formula: C20H15N3O4S
- Molecular Weight:393.42
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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GSK-3β 0.142 μM (IC50) |
HDAC2 0.03 μM (IC50) |
HDAC6 0.045 μM (IC50) |
Chemical Information
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Molecular Weight 393.42
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Formula C20H15N3O4S
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SMILES
O=C(NO)C1=CC=C(CN2C(SN(C3=C(C=CC=C4)C4=CC=C3)C2=O)=O)C=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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