Gymnemagenin
Based on 1 Customer Validation
Gymnemagenin is a triterpenoid isolated from G. sylvestre. Gymnemagenin is an agent for diabetes and obesity and also possesses antiviral properties.
For research use only. We do not sell to patients.
- Purity: 99.61%
- CAS No.: 22467-07-8
- Formula: C30H50O6
- Molecular Weight:506.71
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Storage:
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
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Biological Activity
Gymnemagenin has a short half-life and a high clearance in rats[2].
Gymnemagenin metabolizes rapidly with a short apparent and intrinsic half-life (~ 7 min) and high intrinsic clearance[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 22467-07-8
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Appearance Solid
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Molecular Weight 506.71
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Formula C30H50O6
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Color White to off-white
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SMILES
OC[C@]1([C@H]2O)[C@](CC(C)(C)[C@H]2O)([H])C3=CC[C@@]4([H])[C@@](C)(CC[C@]5([H])[C@@]4(CC[C@H](O)[C@@]5(C)CO)C)[C@]3(C)C[C@@H]1O
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Solvent & Solubility
DMSO : 30 mg/mL (59.21 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (274 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
[1]. Parthasarathy R, et al. Gymnemagenin-producing endophytic fungus isolated from a medicinal plant Gymnema sylvestre R.Br. Appl Biochem Biotechnol. 2014 Mar;172(6):3141-52. [Content Brief]
[2]. In Vitro Metabolic Stability and Permeability of Gymnemagenin and Its In Vivo Pharmacokinetic Correlation in Rats - A Pilot Study. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.9735 mL | 9.8676 mL | 19.7352 mL | 49.3379 mL |
| 5 mM | 0.3947 mL | 1.9735 mL | 3.9470 mL | 9.8676 mL | |
| 10 mM | 0.1974 mL | 0.9868 mL | 1.9735 mL | 4.9338 mL | |
| 15 mM | 0.1316 mL | 0.6578 mL | 1.3157 mL | 3.2892 mL | |
| 20 mM | 0.0987 mL | 0.4934 mL | 0.9868 mL | 2.4669 mL | |
| 25 mM | 0.0789 mL | 0.3947 mL | 0.7894 mL | 1.9735 mL | |
| 30 mM | 0.0658 mL | 0.3289 mL | 0.6578 mL | 1.6446 mL | |
| 40 mM | 0.0493 mL | 0.2467 mL | 0.4934 mL | 1.2334 mL | |
| 50 mM | 0.0395 mL | 0.1974 mL | 0.3947 mL | 0.9868 mL |