HDAC1 Degrader-1
HDAC1 Degrader-1 (compound 1a) is an HDAC1 degrader with anticancer activity. HDAC1 Degrader-1 significantly reduces HDAC1 levels in MM.1S multiple myeloma cells.
For research use only. We do not sell to patients.
- Formula: C26H37N3O4
- Molecular Weight:455.59
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
HDAC1[1]
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| MM1.S | IC50 |
3.97 μM
Compound: 1a
|
Antiproliferative activity against human MM.1S cells assessed as inhibition of cell growth incubated for 72 hrs by microplate photometer analysis
Antiproliferative activity against human MM.1S cells assessed as inhibition of cell growth incubated for 72 hrs by microplate photometer analysis
|
[PMID: 38116436] |
Chemical Information
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Molecular Weight 455.59
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Formula C26H37N3O4
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SMILES
O=C(NCCCCCCC(NO)=O)C1=CC=C(NC(CC2(C3)C[C@@H](C4)C[C@H]3C[C@@H]4C2)=O)C=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)