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Cat. No.: HY-N12228

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Phenelfamycin E

Phenelfamycin E is an elfamycin-type antibiotic. Elfamycin-type antibiotics inhibit protein synthesis by interfering with the function of bacterial elongation factor Tu (F-Tu). Phenelfamycin E has antibacterial activity against Gram-positive anaerobic bacteria, including Clostridioides difficile. Phenelfamycin E can be used in research related to Gram-positive anaerobic bacterial infections.

For research use only. We do not sell to patients.

CAS No.: 114451-31-9
Formula: C₆₅H₉₅NO₂₁
Molecular Weight:1226.44

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (279 KB)

Phenelfamycin E Chemical Structure

CAS No.: 114451-31-9

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
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Biological Activity

Description

All Antibiotic Isoforms :

In Vitro

Bacterial Infection

Phenelfamycin E has antibacterial activity against Gram-positive anaerobic bacteria and no significant activity against Gram-negative bacteria^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Related Protocols :

Chemical Information

CAS No. 114451-31-9
Molecular Weight 1226.44
Formula C₆₅H₉₅NO₂₁
SMILES

CO[C@H]([C@@H]([C@@H](O1)C)O[C@@H]2C[C@H]([C@H]([C@@H](O2)C)O[C@H]3C[C@@H]([C@@H]([C@@H](O3)C)O)OC)OC)C[C@@H]1OC[C@@H]([C@@]4([C@@H]([C@@H](C(C)([C@@H](O4)/C=C/C=C\C)C)O)OC(CC5=CC=CC=C5)=O)O)C(NC/C=C/C=C(C)/[C@@H](OC)[C@H]([C@]6([H])O[C@H]([C@H](C6)O)/C=C/C=C/C=C/C(O)=O)C)=O
Structure Classification
- Antibiotics
- Other Antibiotics
Initial Source
- Microorganism
Streptomyces sp.
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (279 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Brötz E, et al. Phenelfamycins G and H, new elfamycin-type antibiotics produced by Streptomyces albospinus Acta 3619. J Antibiot (Tokyo). 2011 Mar;64(3):257-66. [Content Brief]

[2]. Swanson RN, et al. Phenelfamycins, a novel complex of elfamycin-type antibiotics. III. Activity in vitro and in a hamster colitis model. J Antibiot (Tokyo). 1989 Jan;42(1):94-101.

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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