1. Anti-infection
  2. Bacterial Antibiotic
  3. Hygromycin A

Hygromycin A is a Borrelia burgdorferi-selective antibiotic. Hygromycin A is a spirochete-specific antibacterial that is conducive to gut health. Hygromycin A can be used for Lyme disease research.

For research use only. We do not sell to patients.

Hygromycin A Chemical Structure

Hygromycin A Chemical Structure

CAS No. : 6379-56-2

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1 mg USD 67 In-stock
5 mg USD 200 In-stock
10 mg USD 300 In-stock
25 mg USD 490 In-stock
50 mg USD 780 In-stock
100 mg USD 1250 In-stock
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Based on 1 publication(s) in Google Scholar

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Description

Hygromycin A is a Borrelia burgdorferi-selective antibiotic. Hygromycin A is a spirochete-specific antibacterial that is conducive to gut health. Hygromycin A can be used for Lyme disease research[1].

In Vivo

Hygromycin A selectively kills Borrelia burgdorferi and has a favorable impact on the gut microbiota composition, leading to eubiosis[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

511.48

Formula

C23H29NO12

CAS No.
Appearance

Solid

Color

White to light yellow

SMILES

O[C@H]1[C@@]2([H])[C@@](OCO2)([H])[C@@H]([C@H]([C@H]1NC(/C(C)=C/C3=CC(O)=C(C=C3)O[C@@H]4O[C@@H]([C@H]([C@@H]4O)O)C(C)=O)=O)O)O

Initial Source

Streptomyces hygroscopicus

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (195.51 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.9551 mL 9.7756 mL 19.5511 mL
5 mM 0.3910 mL 1.9551 mL 3.9102 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.9551 mL 9.7756 mL 19.5511 mL 48.8778 mL
5 mM 0.3910 mL 1.9551 mL 3.9102 mL 9.7756 mL
10 mM 0.1955 mL 0.9776 mL 1.9551 mL 4.8878 mL
15 mM 0.1303 mL 0.6517 mL 1.3034 mL 3.2585 mL
20 mM 0.0978 mL 0.4888 mL 0.9776 mL 2.4439 mL
25 mM 0.0782 mL 0.3910 mL 0.7820 mL 1.9551 mL
30 mM 0.0652 mL 0.3259 mL 0.6517 mL 1.6293 mL
40 mM 0.0489 mL 0.2444 mL 0.4888 mL 1.2219 mL
50 mM 0.0391 mL 0.1955 mL 0.3910 mL 0.9776 mL
60 mM 0.0326 mL 0.1629 mL 0.3259 mL 0.8146 mL
80 mM 0.0244 mL 0.1222 mL 0.2444 mL 0.6110 mL
100 mM 0.0196 mL 0.0978 mL 0.1955 mL 0.4888 mL
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Hygromycin A Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Hygromycin A
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