2. Cell Cycle/DNA Damage Anti-infection
  3. Topoisomerase Parasite
  4. Icariside E3

Icariside E3 is a Leishmania donovani DNA Topoisomerase IB (LdTOP1LS) inhibitor. Icariside E3 can be used for the research of leishmaniasis.

For research use only. We do not sell to patients.

Icariside E3

Icariside E3 Chemical Structure

CAS No. : 117613-74-8

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Icariside E3 Related Antibodies

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Description

Icariside E3 is a Leishmania donovani DNA Topoisomerase IB (LdTOP1LS) inhibitor. Icariside E3 can be used for the research of leishmaniasis[1].

In Vitro

Icariside E3 (10-100 μM; 30 min) potently inhibits Leishmania donovani DNA topoisomerase IB (LdTOP1LS)-mediated plasmid relaxation in a dose-dependent manner, achieving 94% inhibition at 50 μM and total inhibition at 100 μM[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Icariside E3 Related Antibodies
Molecular Weight

524.56

Formula

C26H36O11
CAS No.
SMILES

O[C@H]([C@H]([C@@H]([C@@H](CO)O1)O)O)[C@@H]1OC2=C(OC)C=C(CCCO)C=C2C(CC3=CC=C(C(OC)=C3)O)CO
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Icariside E3 Related Classifications

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The dilution calculator equation

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Icariside E3117613-74-8Icariside E 3Icariside E-3TopoisomeraseParasiteDNA Topoisomerase IBLeishmania donovanileishmaniasisLdTOP1LSInhibitorinhibitorinhibit

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