Tyk2-IN-14
Tyk2-IN-14 is a Tyk2 inhibitor that regulates IFNα and IL-23 by inhibiting Tyk2-mediated signal transduction. Tyk2-IN-14 exhibits an IC50 of 0.08 μM against the IL-23 Kit225 reporter gene and an IC50 of 0.09 μM against the IFNα Kit225 reporter gene. IL-23 modulator-1 is applicable to the research of inflammatory diseases and autoimmune diseases.
For research use only. We do not sell to patients.
- CAS No.: 1609392-06-4
- Formula: C18H18N6O3S
- Molecular Weight:398.44
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Tyk2 |
IL-23 0.08 μM (IC50) |
Tyk2-IN-14 (CPD31) inhibits IL-23-induced reporter gene activity in Kit225 T cells with an IC50 of 0.08 μM; it also inhibits IFNα-induced reporter gene activity in Kit225 T cells with an IC50 of 0.09 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1609392-06-4
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Molecular Weight 398.44
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Formula C18H18N6O3S
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SMILES
O=C(NC)C1=NN=C(C=C1NC=2C=CC=CC2S(=O)(=O)C)NC3=NC=CC=C3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Tyk2-IN-14 Related Classifications
HY-184786 Related Classifications
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