NYLTHRQ
NYLTHRQ is a peptide. NYLTHRQ specifically blocks the interaction between sVEGFR1-i13 and β1 integrin, and inhibits the activation of VEGFR1 and VEGFR2. NYLTHRQ inhibits cancer cell proliferation. NYLTHRQ can be used in the research of tumors such as lung squamous cell carcinoma.
For research use only. We do not sell to patients.
- CAS No.: 1004284-41-6
- Formula: C40H62N14O12
- Molecular Weight:931.01
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
All VEGFR Isoforms
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Biological Activity
Description
IC50 & Target
[1]|
VEGFR1 |
VEGFR2 |
In Vitro
NYLTHRQ (10 μg/mL; 72 h) specifically blocks the interaction between sVEGFR1-i13 and β1 integrin in MGH7 cells, inhibits VEGFR activation, and reduces cell proliferation activity[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:MGH7 squamous cell lung carcinoma (SQLC) cells
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Concentration:10 μg/mL
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Incubation Time:72 h
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Result:Prevented the activation of VEGFR1 (Tyr1213) and VEGFR2 (Tyr1214) proteins.
Blocked the increased cell proliferation induced by sVEGFR1-i13-containing conditioned supernatants.
- BrdU Incorporation Assay
- Somatic Cell Culture
- CFSE Dye Dilution Proliferation Assay
- Dye-dilution cell tracking and proliferation staining
- CCK-8/WST-8 Cell Proliferation Assay
- Protocol for Cell Cycle
- Cell Counting-Based Growth Curve Assay
- Colony Formation (Clonogenic) Assay
- Cell Viability Determination by MTT Colorimetric Assay
- EdU Incorporation Assay (Click Chemistry-Based DNA Synthesis Measurement)
- Ki-67 Immunostaining Proliferation Assay
- PCNA Immunodetection Proliferation Assay
- Protocol for Cell Counting and Cell Density Analysis
- MTT Cell Proliferation Assay
Chemical Information
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CAS No. 1004284-41-6
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Molecular Weight 931.01
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Formula C40H62N14O12
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Sequence
Asn-Tyr-Leu-Thr-His-Arg-Gln
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Sequence Shortening
NYLTHRQ
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
NYLTHRQ Related Classifications
HY-P11649 Related Classifications
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