cis-Revumenib
Based on 1 Customer Validation
cis-Revumenib (cis-SNDX-5613) is an isomer of Revumenib (HY-136175). Revumenib (SNDX-5613) is a potent and specific Menin-MLL inhibitor with a binding Ki of 0.149 nM and a cell based IC50 of 10-20 nM. Revumenib can be used for the research of MLL-rearranged (MLL-r) acute leukemias, including acute lymphoblastic leukemia (ALL) and acute myeloid leukemia (AML).
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 98.92%
- 分子式: C32H47FN6O4S
- 分子量:630.82
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保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
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HY-L024
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Anti-Cancer Compound Library
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Reprogramming Compound Library
HY-L039
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Anti-Blood Cancer Compound Library
HY-L079
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Protein-protein Interaction Inhibitor Library
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Highly Selective Inhibitors Library
HY-L158
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Anti-Hematopathy Compound Library
HY-L171
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Bioactive Compound Library Max
HY-L181
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MCE Bioactive Compound Library
HY-L001V
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Bioactive Compound Library
HY-L001
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High-Throughput Bioactive Compound Library
HY-L205
生物活性
化学情報
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性状 Solid
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分子量 630.82
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分子式 C32H47FN6O4S
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Color White to off-white
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SMILES
O=C(N(CC)C(C)C)C1=CC(F)=CC=C1OC2=CN=CN=C2N3CC4(CCN(C[C@H]5CC[C@@H](NS(=O)(CC)=O)CC5)CC4)C3
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別名
cis-SNDX-5613
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
DMSO : 100 mg/mL (158.52 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (272 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.5852 mL | 7.9262 mL | 15.8524 mL | 39.6310 mL |
| 5 mM | 0.3170 mL | 1.5852 mL | 3.1705 mL | 7.9262 mL | |
| 10 mM | 0.1585 mL | 0.7926 mL | 1.5852 mL | 3.9631 mL | |
| 15 mM | 0.1057 mL | 0.5284 mL | 1.0568 mL | 2.6421 mL | |
| 20 mM | 0.0793 mL | 0.3963 mL | 0.7926 mL | 1.9815 mL | |
| 25 mM | 0.0634 mL | 0.3170 mL | 0.6341 mL | 1.5852 mL | |
| 30 mM | 0.0528 mL | 0.2642 mL | 0.5284 mL | 1.3210 mL | |
| 40 mM | 0.0396 mL | 0.1982 mL | 0.3963 mL | 0.9908 mL | |
| 50 mM | 0.0317 mL | 0.1585 mL | 0.3170 mL | 0.7926 mL | |
| 60 mM | 0.0264 mL | 0.1321 mL | 0.2642 mL | 0.6605 mL | |
| 80 mM | 0.0198 mL | 0.0991 mL | 0.1982 mL | 0.4954 mL | |
| 100 mM | 0.0159 mL | 0.0793 mL | 0.1585 mL | 0.3963 mL |
cis-Revumenib 関連分類
HY-136175B 関連分類
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