Dentonin TFA
Dentonin TFA (AC-100 TFA) is a synthetic fragment derived from MEPE. Dentonin TFA enhances osteogenesis by promoting osteoprogenitor adhesion and facilitates immature adherent cells survival. Dentonin TFA has no significant effect to mature osteoblasts. Dentonin TFA can be used for the research of phosphate homeostasis and bone metabolism.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 分子式: C109H161F3N30O44
- 分子量:2652.61
-
保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
MEPE is a a member of the SIBLING (Small Integrin-Binding Ligand, N-linked Glycoprotein) family of secreted glycophosphoproteins.? MEPE ?regulates bone mass and influence osteoblast activity.[1].Dentonin TFA (3-30 μg/ml; 2-24 hours) significantly increases the numbers of cell and shows enhanced promotion of cell adhesion. However, it has no significant differences in terms of numbers of cells adhered[2].Dentonin TFA (3-30 μg/ml; 2-24 hours) enhances osteoblast spreading, it exhibits significantly increased cell areas compared to all other treatment[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
-
分子量 2652.61
-
分子式 C109H161F3N30O44
-
別名
AC-100 TFA
-
シーケンスの短縮
TDLQERGDNDISPFSGDGQPFKD
-
輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
[1]. Andrew P Sprowson, et al. ASARM-truncated MEPE and AC-100 enhance osteogenesis by promoting osteoprogenitor adhesion. J Orthop Res. 2008 Sep;26(9):1256-62. [Content Brief]
[2]. N Six, et al. Dentonin, a MEPE fragment, initiates pulp-healing response to injury.J Dent Res. 2007 Aug;86(8):780-5. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)