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製品番号: HY-135876

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γ-Elemene

Name: γ-Elemene
Brand: MedChemExpress
SKU: HY-135876
Availability: PreOrder

(別名: (-)-γ-Elemene)

γ-Elemene ((-)-γ-Elemene) is a lipid-lowering agent. γ-Elemene increases superoxide dismutase (SOD). γ-Elemene reduces the expression of adhesion molecules (VCAM-1, ICAM-1) in cells damaged by H₂O₂. γ-Elemene regulates lipid peroxidation. γ-Elemene protects cells from peroxidative damage induced by high fat and H₂O₂. γ-Elemene decreases lipid content. γ-Elemene can be used in the research of atherosclerosis.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

CAS 番号: 29873-99-2
分子式: C₁₅H₂₄
分子量:204.36

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (281 KB)

γ-Elemene 構造式

CAS 番号: 29873-99-2

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性

製品説明

Integrin アイソフォーム固有の製品をすべて表示 :

体外実験

Oxidative StressLocal Vascular RegulationLipid Metabolism

Oxidative Stress

γ-Elemene and (-)-γ-Elemene (1 μg/mL; 24 h) exert antioxidant protective effects against H₂O₂-induced oxidative damage in human umbilical vein endothelial cells (HUVEC). The increase rates of superoxide dismutase (SOD) induced by them are 23.75% and 22.45%, respectively, while the decrease rates of malondialdehyde (MDA) are 35.22% and 36.82%, respectively^[1].

Local Vascular Regulation

(-)-γ-Elemene (24 h) reduces the expression of adhesion factors in H₂O₂-injured HUVEC cells, with a reduction rate of 22.87% for VCAM-1 and 15.58% for ICAM-1^[1].

Lipid Metabolism

(-)-γ-Elemene (24 h) reduces intracellular lipid levels in free fatty acid (FFA)-loaded HepG2 cells, with a triglyceride (TG) reduction rate of 21.39% and a non-esterified fatty acid (NEFA) reduction rate of 16.43%^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

ELISA Assay^[1]

Cell Line:

human umbilical vein endothelial cells (HUVEC)
Concentration:

Not specified
Incubation Time:

24 h
Result:

Reduced ICAM-1 levels by 15.58%.
Reduced VCAM-1 levels by 22.87%.

Related Protocols :

化学情報

CAS 番号 29873-99-2
分子量 204.36
分子式 C₁₅H₂₄
SMILES

C(C)(=C)[C@@H]1[C@](C=C)(C)CCC(=C(C)C)C1
別名

(-)-γ-Elemene
Structure Classification
- Terpenoids
- Sesquiterpenes
Initial Source
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション

バッチを選択:

純度: 99.98%

Assay: 99.98%

ee.: 99.98%

データシート (281 KB)
COA (2659 KB)
元素分析報告書 (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
取扱説明書 (2659 KB)

参考文献

[1]. Shang, et al. Use of gamma-elemene and derivatives thereof in preventing atherosclerosis. CN103284979A. China. 2013-06-17.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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