LDV-FITC
Based on 1 Customer Validation
LDV-FITC, a fluorescent peptide, is a FITC-conjugated LDV peptide (HY-P2267). LDV-FITC binds to the α4β1 integrin with high affinity (Kd: 0.3 nM and 12 nM for binding to U937 cells in the presence and absence of Mn2+ respectively). LDV-FITC can be used to detect α4β1 integrin affinity.
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 98.13%
- CAS 番号: 1207610-07-8
- 分子式: C69H81N11O17S
- 分子量:1368.51
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保管条件:
Sealed storage, away from moisture.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
α4β1 integrin[1]
化学情報
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CAS 番号 1207610-07-8
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性状 Solid
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分子量 1368.51
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分子式 C69H81N11O17S
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Color Light yellow to yellow
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配列
{4-((N′-2-methylphenyl)ureido)-phenylacetyl}-Leu-Asp-Val-Pro-Ala-Ala-{Lys(FITC)}
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シーケンスの短縮
{4-((N′-2-methylphenyl)ureido)-phenylacetyl}-LDVPAA-{Lys(FITC)}
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Sealed storage, away from moisture
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
溶剤 & 溶解度
DMSO : 100 mg/mL (73.07 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (279 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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取扱説明書 (2659 KB)
参考文献
[1]. Hyduk SJ, et al. Phospholipase C, calcium, and calmodulin are critical for alpha4beta1 integrin affinity up-regulation and monocyte arrest triggered by chemoattractants. Blood. 2007 Jan 1;109(1):176-84. [Content Brief]
[2]. Chigaev A, et al. Real time analysis of the affinity regulation of alpha 4-integrin. The physiologically activated receptor is intermediate in affinity between resting and Mn(2+) or antibody activation. J Biol Chem. 2001 Dec 28;276(52):48670-8. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 0.7307 mL | 3.6536 mL | 7.3072 mL | 18.2680 mL |
| 5 mM | 0.1461 mL | 0.7307 mL | 1.4614 mL | 3.6536 mL | |
| 10 mM | 0.0731 mL | 0.3654 mL | 0.7307 mL | 1.8268 mL | |
| 15 mM | 0.0487 mL | 0.2436 mL | 0.4871 mL | 1.2179 mL | |
| 20 mM | 0.0365 mL | 0.1827 mL | 0.3654 mL | 0.9134 mL | |
| 25 mM | 0.0292 mL | 0.1461 mL | 0.2923 mL | 0.7307 mL | |
| 30 mM | 0.0244 mL | 0.1218 mL | 0.2436 mL | 0.6089 mL | |
| 40 mM | 0.0183 mL | 0.0913 mL | 0.1827 mL | 0.4567 mL | |
| 50 mM | 0.0146 mL | 0.0731 mL | 0.1461 mL | 0.3654 mL | |
| 60 mM | 0.0122 mL | 0.0609 mL | 0.1218 mL | 0.3045 mL |
LDV-FITC 関連分類
HY-P1188 関連分類
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