Pulixin
Pulixin prevents FREP1 from binding to P. falciparum-infected cell lysate. Pulixin blocks the transmission of the parasite to mosquitoes with an EC50 of 11 µM. Pulixin also inhibits the proliferation of asexual-stage P. falciparum with an EC50 of 47 nM.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 2826264-81-5
- 分子式: C14H11NO4
- 分子量:257.24
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
製品説明
IC50 & Target
[1]|
Plasmodium |
Microbial Metabolite |
体外実験
Pulixin, a fungal metabolite, inhibits Plasmodium falciparum transmission and infection. It does not show cytotoxic effects at a concentration of 116 µM or lower[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 2826264-81-5
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分子量 257.24
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分子式 C14H11NO4
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SMILES
O=C1C2=C(O)C=C(O)C=C2C3=C(O1)C=C(N)C=C3C
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Structure Classification
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Initial Source
Purpureocillium lilacinum
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)