UK-2A
UK-2A (Antibiotic UK 2A) is a potent antifungal antibiotic. UK-2A shows antifungal activity.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 167173-85-5
- 分子式: C26H30N2O9
- 分子量:514.52
-
保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
生物活性
-
化学情報
- 純度とドキュメンテーション
- 参考文献
-
Help & FAQs
Antibiotic アイソフォーム固有の製品をすべて表示
More
生物活性
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| RBL-2H3 | IC50 |
1377 nM
Compound: 1; UK-2A
|
Anti-inflammatory activity in DNP-IgE-stimulated rat RBL2H3 cells assessed as reduction of IL4 secretion pretreated for 10 mins followed by DNP-HSA stimulation measured after 1 hr by ELISA
Anti-inflammatory activity in DNP-IgE-stimulated rat RBL2H3 cells assessed as reduction of IL4 secretion pretreated for 10 mins followed by DNP-HSA stimulation measured after 1 hr by ELISA
|
[PMID: 30417645] |
UK-2A (0-100 µg/mL; 24, 48, 120 h) shows antifungal activity against R. mucilaginosa IFO 0001 with MICs of 1.56, >100, >100 µg/mL at 24, 48, 120 h, respectively[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
-
CAS 番号 167173-85-5
-
分子量 514.52
-
分子式 C26H30N2O9
-
SMILES
CC(C)C(O[C@H]([C@H]1CC2=CC=CC=C2)[C@H](C)OC([C@@H](NC(C3=NC=CC(OC)=C3O)=O)COC1=O)=O)=O
-
別名
Antibiotic UK 2A
-
Structure Classification
-
Initial Source
Streptomyces sp.
-
輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
[1]. Ueki M, et al. UK-2A, B, C and D, novel antifungal antibiotics from Streptomyces sp. 517-02. I. Fermentation, isolation, and biological properties. J Antibiot (Tokyo). 1996 Jul;49(7):639-43. [Content Brief]
[2]. Tani K, et al. UK-2A, B, C, and D, novel antifungal antibiotics from Streptomyces sp. 517-02 VII. Membrane injury induced by C9-UK-2A, a derivative of UK-2A, in Rhodotorula mucilaginosa IFO 0001. J Antibiot (Tokyo). 2002 Mar;55(3):315-21. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
UK-2A 関連分類
HY-19965 関連分類
Powered by Bioz