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ZD-1-186

ZD-1-186 is a nondegradative molecular glue that potently suppresses MYC and robustly induces CDKN1A (p21) in diffuse large B-cell lymphoma cells. ZD-1-186 brings together BCL6 with BRD9, a noncanonical BAF complex bromodomain protein implicated in maintaining MYC transcriptional output in specific lymphoma contexts. ZD-1-186 can be used for targeted transcriptional rewiring research.

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  • 分子式: C35H37ClFN9O5S
  • 分子量:750.24
  • 保管条件:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • ZD-1-186 Chemical Structure
    ZD-1-186 構造式
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  • ZD-1-186 Chemical Structure
    ZD-1-186 Chemical Structure
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  • ZD-1-186