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Resiquimod

(Synonyms: R848; S28463)
116 Cited Publications
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Based on 116 publication(s) in Google Scholar

Resiquimod is a Toll-like receptor 7 and 8 (TLR7/TLR8) agonist that induces the upregulation of cytokines such as TNF-α, IL-6 and IFN-α.

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  • Purity: 99.87%
  • CAS No.: 144875-48-9
  • 화학식: C17H22N4O2
  • 분자량:314.39
  • 보관:
    Powder   -20°C, 3 years , 4°C, 2 years ; In solvent   -80°C, 1 year , -20°C, 6 months
  • Resiquimod Chemical Structure
    Resiquimod Chemical Structure
  • Experimental Validation Results for Resiquimod
  • Experimental Validation Results for Resiquimod
  • Experimental Validation Results for Resiquimod
CAS No.: 144875-48-9
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Cell Proliferation/Viability AssayRT-PCRWB
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  • Cell Proliferation/Viability Assay
  • RT-PCR

All Toll-like Receptor (TLR) Isoforms

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  • Resiquimod Chemical Structure
    Resiquimod Chemical Structure
    1/16
  • 1/16

    Resiquimod purchased from MedChemExpress. Usage Cited in: Cancer Gene Ther. 2023 Jun;30(6):866-877. [Abstract]

    Customer Validation
     Resiquimod (10-200 μM) reduces E-cadherin and Wnt5a expression in a dose-dependent manner.

  • 1/16

    Resiquimod purchased from MedChemExpress. Usage Cited in: Cytokine. 2017 Nov:99:310-315. [Abstract]

    Customer Validation
     IL-23 production by macrophages after stimulation with LPS or Resiquimod M1 macrophages (day 9) were stimulated with LPS (10 ng) or Resiquimod (5 μM) for 6 h and IL-23 protein is measured by ELISA.

  • 1/16

    Resiquimod purchased from MedChemExpress. Usage Cited in: J Interferon Cytokine Res. 2016 Sep;36(9):563-72. [Abstract]

    Customer Validation
     With the stimulus of agonists LPS, ODN2006, Poly (I: C), and R848, the mRNA levels of goOASL in PBMCs are significantly upregulated in LPS- and Poly (I: C)-treated groups, and extremely upregulated in ODN2006- and R848-treated groups.

  • Resiquimod