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Cat. No.: HY-132807

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Amdizalisib

(Synonyms: HMPL-689)

Amdizalisib (HMPL-689) is a PI3K inhibitor and used for the research of inflammatory disease, autoimmune disease or cancer.

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CAS No.: 1894229-05-0
화학식: C₁₉H₁₅ClN₈
분자량:390.83

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (272 KB)

Amdizalisib Chemical Structure

CAS No.: 1894229-05-0

사이즈

가격

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수량

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- Cellular Effect
- Clinical Trial
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

Amdizalisib (HMPL-689) is a PI3K inhibitor and used for the research of inflammatory disease, autoimmune disease or cancer^[1].

All PI3K Isoforms :

Cellular Effect

Cell Line	Type	Value	Description	References
Sf21	IC₅₀	0.3 nM Compound: 28	Inhibition of N-terminal His6-tagged recombinant full length human p110delta/untagged recombinant full length human p85alpha expressed in baculovirus infected Sf21 insect cells after 80 mins by fluorescence polarization assay Inhibition of N-terminal His6-tagged recombinant full length human p110delta/untagged recombinant full length human p85alpha expressed in baculovirus infected Sf21 insect cells after 80 mins by fluorescence polarization assay	[PMID: 30582813]

Clinical Trial

NCT Number	Sponsor	Condition	Start Date	Phase A549
NCT01329991	Plexxikon\|		2011-05	PHASE1

Chemical Information

CAS No. 1894229-05-0
분자량 390.83
화학식 C₁₉H₁₅ClN₈
SMILES

N#CC(C(N[C@H](C1=CC2=NC=C(Cl)N2N=C1C3=CC=CC=C3)C)=NC=N4)=C4N
Synonyms

HMPL-689
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (272 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Su, Wei-Guo, et al.Preparation of imidazopyridazine compounds as PI3K inhibitors and their use.WO2016045591A1.

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

MOQ

Minimum order quantity

100 mg

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Amount: USD 0.00

Biological Activity
- 제품 설명
- Clinical Trial
Chemical Information
순도&문서
References

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수량:
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Amdizalisib

All PI3K Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

Amdizalisib Related Classifications

HY-132807 Related Classifications