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Cat. No.: HY-119996

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AR-C141990

1 Cited Publications

고객리뷰

AR-C141990 (Compound 30) is a potent blocker of the monocarboxylate transporter MCT1 with a K_i of 4.8 nM. AR-C141990 (Compound 30) inhibits CYP3A4 and CYP2C9 with IC₅₀ values of 16 μM.

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CAS No.: 873327-59-4
화학식: C₂₆H₂₈N₄O₄S
분자량:492.59

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (273 KB)

AR-C141990 Chemical Structure

CAS No.: 873327-59-4

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

제품 설명

AR-C141990 (Compound 30) is a potent blocker of the monocarboxylate transporter MCT1 with a K_i of 4.8 nM. AR-C141990 (Compound 30) inhibits CYP3A4 and CYP2C9 with IC₅₀ values of 16 μM^[1].

All Monocarboxylate Transporter Isoforms :

All Cytochrome P450 Isoforms :

Chemical Information

CAS No. 873327-59-4
분자량 492.59
화학식 C₂₆H₂₈N₄O₄S
SMILES

O=C1N(CC(C)C)C2=C(C(C(N3C[C@H](O)CC3)=O)=C(CC4=CC=NC5=CC=CC=C45)S2)C(N1C)=O
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

Publications (1)

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Journal Impact Factor

Cell Death Differ

Transcription factor Zhx2 is a checkpoint that programs macrophage polarization and antitumor response. [Abstract]

2023 Sep;30(9):2104-2119. PMID: 37582865

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (273 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Guile SD, et al. Potent blockers of the monocarboxylate transporter MCT1: novel immunomodulatory compounds. Bioorg Med Chem Lett. 2006 Apr 15;16(8):2260-5. [Content Brief]

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

AR-C141990

1 Cited Publications

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Biological Activity
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Chemical Information
Publications (1)
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AR-C141990

Publications Citing Use of MedChemExpress (MCE) AR-C141990

All Monocarboxylate Transporter Isoforms

All Cytochrome P450 Isoforms

Biological Activity

Chemical Information

Publications (1)

순도&문서

References

Calculators

Help & FAQs

AR-C141990 Related Classifications

Cat. No.: HY-119996