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Aripiprazole monohydrate

(Synonyms: OPC-14597 monohydrate)
11 Cited Publications
고객리뷰

Based on 11 publication(s) in Google Scholar

Aripiprazole (OPC-14597) monohydrate, an atypical antipsychotic, is a potent and high-affinity dopamine D2 receptor partial agonist. Aripiprazole monohydrate is an inverse agonist at 5-HT2B and 5-HT2A receptors and displays partial agonist actions at 5-HT1A, 5-HT2C, D3, and D4 receptors. Aripiprazole monohydrate can be used for the research of schizophrenia and COVID19.

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  • Purity: 99.83%
  • CAS No.: 851220-85-4
  • 화학식: C23H29Cl2N3O3
  • 분자량:466.40
  • 보관:

    4°C, sealed storage, away from moisture and light

    * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

  • Aripiprazole monohydrate Chemical Structure
    Aripiprazole monohydrate Chemical Structure
  • Experimental Validation Results for Aripiprazole monohydrate
  • Experimental Validation Results for Aripiprazole monohydrate
  • Experimental Validation Results for Aripiprazole monohydrate
  • Experimental Validation Results for Aripiprazole monohydrate
  • Experimental Validation Results for Aripiprazole monohydrate
CAS No.: 851220-85-4
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  • Aripiprazole monohydrate Chemical Structure
    Aripiprazole monohydrate Chemical Structure
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  • 1/16

    Aripiprazole monohydrate purchased from MedChemExpress. Usage Cited in: CNS Neurosci Ther. 2024 May;30(5):e14739. [Abstract]

    Customer Validation
     We evaluated the therapeutic effects of Aripiprazole (1 mg/kg, ip, single dose) on the electrophysiological activities of MK‐801‐treated mice.

  • 1/16

    Aripiprazole monohydrate purchased from MedChemExpress. Usage Cited in: CNS Neurosci Ther. 2024 May;30(5):e14739. [Abstract]

    Customer Validation
     In the MK-801 group, theta power was significantly reduced by Aripiprazole (1 mg/kg, ip, single dose) treatment.

  • 1/16

    Aripiprazole monohydrate purchased from MedChemExpress. Usage Cited in: CNS Neurosci Ther. 2024 May;30(5):e14739. [Abstract]

    Customer Validation
     The spontaneous spike activity of RS and FS units were significantly reduced by Aripiprazole (1 mg/kg, ip, single dose) treatment in the MK-801 group.

  • 1/16

    Aripiprazole monohydrate purchased from MedChemExpress. Usage Cited in: Int J Mol Sci. 2024 Jan 14;25(2):1035. [Abstract]

    Customer Validation
     Histogram showing the average percentage of change from the vehicle/vehicle-treated group for the PLF of the gamma-band ASSR recorded in rats' global cortex following an acute administration with Aripiprazole (0 and 3 mg/kg) and MK-801 in comparison with vehicle/vehicle-treated animals and MK-801/vehicle-treated animals.

  • 1/16

    Aripiprazole monohydrate purchased from MedChemExpress. Usage Cited in: Int J Mol Sci. 2024 Jan 14;25(2):1035. [Abstract]

    Customer Validation
     Horizontal activity plotted over 240 min following an acute administration with Aripiprazole (Ari) at 1, 3, 10 and 30 mg/kg in MK-801-treated rats in comparison with vehicle (Veh)/vehicle-treated, MK-801/vehicle-treated or MK-801/clozapine (Cloza)-treated rats (clozapine being used as a positive control).

  • Aripiprazole monohydrate