Azinomycin A
Azinomycin A is an antitumor antibiotic. Azinomycin A exhibits cytotoxic activity and antitumor effects against murine tumors. Azinomycin A shows antibacterial activity against Gram-negative and Gram-positive bacteria. Azinomycin A can be used for research on leukemia and bacterial infections.
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- CAS No.: 106486-77-5
- 화학식: C30H33N3O10
- 분자량:595.60
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
All Antibiotic Isoforms
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Biological Activity
제품 설명
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| L5178Y | IC50 |
0.07 mg/mL
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Cytotoxicity against murine L5178Y leukemia cells.
Cytotoxicity against murine L5178Y leukemia cells.
|
21327255 |
In Vitro
Azinomycin A shows potent in vitro cytotoxic activity against L5178Y murine leukemia cells with an IC50 of 0.07 μg/mL[1].
Azinomycin A exhibits antibacterial activity against Staphylococcus aureus with an MIC of 6.25 μg/mL and against Klebsiella pneumonia ATCC 10031 with an MIC of 3.13 μg/mL[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 106486-77-5
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분자량 595.60
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화학식 C30H33N3O10
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SMILES
O=C(C1=CC(OC)=CC2=C1C=CC=C2C)O[C@@H]([C@@]3(CO3)C)C(N/C(C(NCC(C)=O)=O)=C4N5[C@@]([C@H]([C@@H]/4OC(C)=O)O)([H])C5)=O
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Structure Classification
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Initial Source
Streptomyces sahachiroi
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Keywords
- Azinomycin A
- 106486-77-5
- Antibiotic
- Bacterial
- Klebsiella pneumonia ATCC 10031
- cytotoxic activity
- DNA interstrand cross-linking agent
- guanine N7 residues
- L5178Y murine leukemia cells
- double-strand breakage
- antitumor effects
- antibacterial activity
- Staphylococcus aureus
- Gram-negative and Gram-positive bacteria
- Inhibitor
- inhibitor
- inhibit