Docarpamine
Docarpamine is an orally active dopamine prodrug that can be hydroxylated in the small intestine and liver to form active dopamine. Docarpamine mainly activates D1-like receptors in peripheral blood vessels to lower blood pressure and heart rate in a state of spontaneous hypertension. Docarpamine exerts a pressor and tachycardic effect by activating D1-like receptors, vasopressin V1 receptors, and α-adrenergic receptors in normal blood pressure conditions. Docarpamine can be used for research on renal vascular dilation and diuresis.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- CAS No.: 74639-40-0
- 화학식: C21H30N2O8S
- 분자량:470.54
-
보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
All Dopamine Receptor Isoforms
MoreAll Vasopressin Receptor Isoforms
MoreAll Adrenergic Receptor Isoforms
More
Biological Activity
제품 설명
IC50 & Target
[1]|
D1 Receptor |
α adrenergic receptor |
Chemical Information
-
CAS No. 74639-40-0
-
분자량 470.54
-
화학식 C21H30N2O8S
-
SMILES
CCOC(OC1=C(C=C(C=C1)CCNC([C@@H](NC(C)=O)CCSC)=O)OC(OCC)=O)=O
-
선적
Room temperature in continental US; may vary elsewhere.
-
보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
[1]. Sanada H, et al. The effect of docarpamine, a dopamine pro-drug, on blood pressure and catecholamine levels in spontaneously hypertensive rats. Clin Exp Hypertens. 2000 May;22(4):419-29. [Content Brief]
[2]. Tsunoda T, et al. Treatment for ovarian hyperstimulation syndrome using an oral dopamine prodrug, docarpamine. Gynecol Endocrinol. 2003 Aug;17(4):281-6. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)