Ethopropazine
Based on 1 publication(s) in Google Scholar
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- CAS No.: 522-00-9
- 화학식: C19H24N2S
- 분자량:312.48
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Chemical Information
- 순도&문서
- References
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Publications Citing Use of MedChemExpress (MCE) Ethopropazine
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Biological Activity
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HEK293 | IC50 |
20.46 μM
Compound: Ethopropazine
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Inhibition of human OCT1 expressed in HEK293 cells assessed as decrease in uptake of ASP+ after 2 mins by fluorescence assay
Inhibition of human OCT1 expressed in HEK293 cells assessed as decrease in uptake of ASP+ after 2 mins by fluorescence assay
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[PMID: 28230985] |
| NCI-H1650 | GI50 |
>40 μM
Compound: Ethopropazine
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Cytotoxicity against human NCI-H1650 cells assessed as growth inhibition after 48 hrs by MTT assay
Cytotoxicity against human NCI-H1650 cells assessed as growth inhibition after 48 hrs by MTT assay
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[PMID: 26372073] |
Chemical Information
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CAS No. 522-00-9
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분자량 312.48
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화학식 C19H24N2S
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SMILES
S1C=2C=CC=CC2N(C=3C=CC=CC13)CC(N(CC)CC)C
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Synonyms
Isothazine free base
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (1)
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Journal Impact Factor
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Most Recent
순도&문서
References
[1]. Giladi N, et al. Toxicity of the specific antimuscarinic agent methoctramine and other non-specific anticholinergic drugs in human neuroblastoma cell lines in vitro. Toxicol In Vitro. 1993 Sep;7(5):595-603. [Content Brief]
[2]. Inazu M, et al. Functional expression of choline transporter-like protein 1 (CTL1) in small cell lung carcinoma cells: a target molecule for lung cancer therapy. Pharmacol Res. 2013 Oct;76:119-31. [Content Brief]
[3]. Jevtovic-Todorovic V, et al. Anti-parkinsonian agents procyclidine and ethopropazine alleviate thermal hyperalgesia in neuropathic rats. Neuropharmacology. 2003 May;44(6):739-48. [Content Brief]
[4]. Sinko G, et al. Mechanism of stereoselective interaction between butyrylcholinesterase and ethopropazine enantiomers. Biochimie. 2011 Oct;93(10):1797-807. [Content Brief]
[5]. V. Debbeti, et al. Transition Metal Complexes of Ethopropazine: Synthesis and Characterization
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Ethopropazine Related Classifications
HY-107922A Related Classifications
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