FD2056
FD2056 is a potent and orally active PI3K inhibitor. FD2056 inhibits PI3Kα/PI3Kβ/PI3Kγ/PI3Kδ with IC50s of 0.30, 0.80, 1.10, 0.42 nM. FD2056 also inhibits CDK2-CyclinA2 and CDK4-CyclinD3 with IC50 of 115.95 and 2782.15 nM. FD2056 inhibits breast cancer cell proliferation with IC50s of 1.06, 0.04, 1.40 μM for MDA-MB-231, MDA-MB-468, MCF-7 cells. FD2056 also induces cancer apoptosis and inhibits tumor growth.
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- CAS No.: 2685870-87-3
- 화학식: C23H17ClN6O2S
- 분자량:476.94
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
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Biological Activity
Chemical Information
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CAS No. 2685870-87-3
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분자량 476.94
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화학식 C23H17ClN6O2S
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SMILES
O=S(C1=CC=CC=C1)(NC2=CC(C3=CN=C(NC=C4C5=CC(N)=NC=C5)C4=C3)=CN=C2Cl)=O
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
FD2056 Related Classifications
HY-155180 Related Classifications
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