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Cat. No.: HY-135876

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γ-Elemene

Name: γ-Elemene
Brand: MedChemExpress
SKU: HY-135876
Availability: PreOrder

(Synonyms: (-)-γ-Elemene)

γ-Elemene ((-)-γ-Elemene) is a lipid-lowering agent. γ-Elemene increases superoxide dismutase (SOD). γ-Elemene reduces the expression of adhesion molecules (VCAM-1, ICAM-1) in cells damaged by H₂O₂. γ-Elemene regulates lipid peroxidation. γ-Elemene protects cells from peroxidative damage induced by high fat and H₂O₂. γ-Elemene decreases lipid content. γ-Elemene can be used in the research of atherosclerosis.

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CAS No.: 29873-99-2
화학식: C₁₅H₂₄
분자량:204.36

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (281 KB)

γ-Elemene Chemical Structure

CAS No.: 29873-99-2

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Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- In Vitro
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

All Integrin Isoforms :

In Vitro

Oxidative StressLocal Vascular RegulationLipid Metabolism

Oxidative Stress

γ-Elemene and (-)-γ-Elemene (1 μg/mL; 24 h) exert antioxidant protective effects against H₂O₂-induced oxidative damage in human umbilical vein endothelial cells (HUVEC). The increase rates of superoxide dismutase (SOD) induced by them are 23.75% and 22.45%, respectively, while the decrease rates of malondialdehyde (MDA) are 35.22% and 36.82%, respectively^[1].

Local Vascular Regulation

(-)-γ-Elemene (24 h) reduces the expression of adhesion factors in H₂O₂-injured HUVEC cells, with a reduction rate of 22.87% for VCAM-1 and 15.58% for ICAM-1^[1].

Lipid Metabolism

(-)-γ-Elemene (24 h) reduces intracellular lipid levels in free fatty acid (FFA)-loaded HepG2 cells, with a triglyceride (TG) reduction rate of 21.39% and a non-esterified fatty acid (NEFA) reduction rate of 16.43%^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

ELISA Assay^[1]

Cell Line:

human umbilical vein endothelial cells (HUVEC)
Concentration:

Not specified
Incubation Time:

24 h
Result:

Reduced ICAM-1 levels by 15.58%.
Reduced VCAM-1 levels by 22.87%.

Related Protocols :

Chemical Information

CAS No. 29873-99-2
분자량 204.36
화학식 C₁₅H₂₄
SMILES

C(C)(=C)[C@@H]1[C@](C=C)(C)CCC(=C(C)C)C1
Synonyms

(-)-γ-Elemene
Structure Classification
- Terpenoids
- Sesquiterpenes
Initial Source
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (281 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Shang, et al. Use of gamma-elemene and derivatives thereof in preventing atherosclerosis. CN103284979A. China. 2013-06-17.

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

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MOQ

Minimum order quantity

100 mg

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