Hygromycin A
Based on 1 Customer Validation
Hygromycin A is a Borrelia burgdorferi-selective antibiotic. Hygromycin A is a spirochete-specific antibacterial that is conducive to gut health. Hygromycin A can be used for Lyme disease research.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- Purity : 96.78%
- CAS No.: 6379-56-2
- 화학식: C23H29NO12
- 분자량:511.48
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보관:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
All Antibiotic Isoforms
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Biological Activity
제품 설명
In Vivo
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 6379-56-2
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Appearance Solid
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분자량 511.48
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화학식 C23H29NO12
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Color White to light yellow
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SMILES
O[C@H]1[C@@]2([H])[C@@](OCO2)([H])[C@@H]([C@H]([C@H]1NC(/C(C)=C/C3=CC(O)=C(C=C3)O[C@@H]4O[C@@H]([C@H]([C@@H]4O)O)C(C)=O)=O)O)O
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Structure Classification
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Initial Source
Streptomyces hygroscopicus
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선적
Room temperature in continental US; may vary elsewhere.
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보관
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
용액&용해도
In Vitro:
DMSO : 100 mg/mL (195.51 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Protocol
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Research Protocol for Infectious Diseases
Infectious-disease experiments test how pathogens interact with host barriers, innate immune receptors, inflammatory signaling, pathogen replication, and tissue injury; pattern-recognition receptors such as TLRs, RIG-I-like receptors, NOD-like receptors, and inflammasomes detect microbial molecules and activate NF-κB, interferon, and cytokine responses. The central hypothesis is that infection severity reflects the balance between pathogen burden and host response: protective inflammation restricts pathogen growth, whereas excessive or mislocalized inflammation contributes to tissue damage and disease phenotype. Unresolved questions include which host pathways are protective versus pathogenic, why some infection models fail to translate to human disease, and which combined readouts best predict clinically relevant infection outcomes.
순도&문서
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Data Sheet (273 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.9551 mL | 9.7756 mL | 19.5511 mL | 48.8778 mL |
| 5 mM | 0.3910 mL | 1.9551 mL | 3.9102 mL | 9.7756 mL | |
| 10 mM | 0.1955 mL | 0.9776 mL | 1.9551 mL | 4.8878 mL | |
| 15 mM | 0.1303 mL | 0.6517 mL | 1.3034 mL | 3.2585 mL | |
| 20 mM | 0.0978 mL | 0.4888 mL | 0.9776 mL | 2.4439 mL | |
| 25 mM | 0.0782 mL | 0.3910 mL | 0.7820 mL | 1.9551 mL | |
| 30 mM | 0.0652 mL | 0.3259 mL | 0.6517 mL | 1.6293 mL | |
| 40 mM | 0.0489 mL | 0.2444 mL | 0.4888 mL | 1.2219 mL | |
| 50 mM | 0.0391 mL | 0.1955 mL | 0.3910 mL | 0.9776 mL | |
| 60 mM | 0.0326 mL | 0.1629 mL | 0.3259 mL | 0.8146 mL | |
| 80 mM | 0.0244 mL | 0.1222 mL | 0.2444 mL | 0.6110 mL | |
| 100 mM | 0.0196 mL | 0.0978 mL | 0.1955 mL | 0.4888 mL |