Isethionic acid (80% in water)
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Isethionic acid (2-Hydroxyethanesulfonic acid) is an endogenous mammalian Taurine (HY-B0351) metabolite. Isethionic acid forms covalent ester linkages with cholic acid. It acts as a larval settlement inhibitor for Balanus amphitrite with larval toxicity. Isethionic acid enables the low-temperature synthesis of highly hygroscopic water-soluble sulfonates, and its acylated derivatives serve as acidic wetting solubilizers. It is used in studies related to hepatic bile acid metabolism, biological control and organic synthesis.
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- Purity : 80.00%
- CAS No.: 107-36-8
- 화학식: C2H6O4S
- 분자량:126.13
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보관:
Solution, -20°C, 2 years
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Biological Activity
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Chemical Information
- 순도&문서
- References
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Help & FAQs
Biological Activity
제품 설명
In Vitro
Isethionic acid inhibits the attachment of Balanus amphitrite cyprids in a concentration-dependent manner in an in vitro seawater bioassay system, and larval mortality increases at concentrations above 0.01 mg/mL[1].
Isethionic acid can undergo an enzymatic reaction with bile acids under the catalysis of rat liver microsomal preparations to form choyl-ethanesulfonic acid through ester bonds[3].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
In Vivo
Isethionic acid has a higher distribution in cardiac tissue than in muscle at the injection site[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 107-36-8
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Appearance Liquid
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분자량 126.13
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화학식 C2H6O4S
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Color Colorless to light yellow
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SMILES
O=S(CCO)(O)=O
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Synonyms
2-Hydroxyethanesulfonic acid
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Structure Classification
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Solution, -20°C, 2 years
순도&문서
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Data Sheet (268 KB)
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SDS (615 KB)
- English - EN (615 KB)
- Français - FR (615 KB)
- Deutsch - DE (615 KB)
- Norwegian - NO (615 KB)
- Español - ES (615 KB)
- Swedish - SV (615 KB)
- Italian - IT (615 KB)
- Korean - KR (615 KB)
- Portuguese - PT (615 KB)
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Handling Instructions (2659 KB)
References
[1]. Hellio C, et al. Isethionic acid and floridoside isolated from the red alga, Grateloupia turuturu, inhibit settlement of Balanus amphitrite cyprid larvae. Biofouling. 2004 Jun;20(3):139-45. [Content Brief]
[3]. Lombardini JB. Enzymatic formation of a cholic acid derivative of isethionic acid. Biochem Pharmacol. 1976 Mar 15;25(6):717-21. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Isethionic acid (80% in water) Related Classifications
HY-Y0095 Related Classifications
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Keywords
- Isethionic acid (80% in water)
- 107-36-8
- 2-Hydroxyethanesulfonic acid
- Endogenous Metabolite
- Parasite
- Balanus amphitrite cyprid larvae
- rat liver microsomal preparations
- Balanus amphitrite nauplius larvae
- Grateloupia turuturu
- cholic acid
- giant squid axoplasm
- taurine
- white mice
- rats
- mammalian tissues
- Inhibitor
- inhibitor
- inhibit