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Cat. No.: HY-14388

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PF-232798

PF-232798 is an orally active CCR5 antagonist with anti-HIV effects.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

CAS No.: 849753-15-7
화학식: C₂₉H₄₀FN₅O₂
분자량:509.66

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

PF-232798 Chemical Structure

CAS No.: 849753-15-7

사이즈

가격

재고

수량

Amount: USD 0.00

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- Cellular Effect
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

PF-232798 is an orally active CCR5 antagonist with anti-HIV effects^[1].

All CCR Isoforms :

All HIV Isoforms :

Cellular Effect

Cell Line	Type	Value	Description	References
HEK293	IC₅₀	12 μM Compound: 41f, PF-232798	Displacement of [3H]-dofetilide from human ERG expressed in HEK293 cells Displacement of [3H]-dofetilide from human ERG expressed in HEK293 cells	[PMID: 21128663]

Chemical Information

CAS No. 849753-15-7
분자량 509.66
화학식 C₂₉H₄₀FN₅O₂
SMILES

CC1=NC(CN(CC2)C(C(C)C)=O)=C2N1[C@H]3C[C@]4([H])N([C@](CC4)([H])C3)CC[C@@H](C5=CC(F)=CC=C5)NC(C)=O
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Ya Zhu, et al. Molecular binding mode of PF-232798, a clinical anti-HIV candidate, at chemokine receptor CCR5. Acta Pharmacol Sin. 2019 Apr;40(4):563-568. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

MOQ

Minimum order quantity

100 mg

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Amount: USD 0.00

Biological Activity
- 제품 설명
Chemical Information
순도&문서
References

상품명:
Cat. No.:
수량:
MCE Japan Authorized Agent:

상품명:
CAS No.:
Species:
Purity:
수량:

PF-232798

All CCR Isoforms

All HIV Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

PF-232798 Related Classifications

HY-14388 Related Classifications