Pyridomycin
Pyridomycin (Erizomycin) is a selective and low cytotoxic inhibitor of Mycobacterium tuberculosis that effectively targets InhA. Pyrdomycin is also an antibiotic that can be obtained from metabolites of Dactylosporangium fulvum. Pyrdomycin can be used in the study of bacterial infections such as tuberculosis.
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- CAS No.: 18791-21-4
- 화학식: C27H32N4O8
- 분자량:540.56
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- 순도&문서
- References
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Help & FAQs
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Biological Activity
Pyridomycin shows good inhibitory activity against Mycobacterium tuberculosis (minimum inhibitory concentration=0.39 µg/mL)[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 18791-21-4
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분자량 540.56
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화학식 C27H32N4O8
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SMILES
O=C(C1=NC=CC=C1O)N[C@H](C(N[C@@H](CC2=CC=CN=C2)[C@@H](O)[C@H]3C)=O)[C@@H](C)OC(/C(OC3=O)=C(C)/CC)=O
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Synonyms
Erizomycin; NSC 246134
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Structure Classification
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Initial Source
Streptomyces
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
[1]. Hartkoorn RC, et al. Towards a new tuberculosis drug: pyridomycin - nature's isoniazid. EMBO Mol Med. 2012 Oct;4(10):1032-42. [Content Brief]
[2]. Hartkoorn RC, et al. Pyridomycin bridges the NADH- and substrate-binding pockets of the enoyl reductase InhA. Nat Chem Biol. 2014 Feb;10(2):96-8. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pyridomycin Related Classifications
HY-111402 Related Classifications
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