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Cat. No.: HY-121500

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(S,S)-R116010

(S,S)-R116010 is a (S,S)-enantiomer of R116010 (HY-121500A). R116010 is a retinoic acid (RA) metabolism inhibitor and can inhibit hydroxylase CYP26. (S,S)-R116010 shows antitumor effects.

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CAS No.: 355860-40-1
화학식: C₂₁H₂₃N₅S
분자량:377.51

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (284 KB)

(S,S)-R116010 Chemical Structure

CAS No.: 355860-40-1

Amount: USD 0.00

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- IC₅₀ & Target
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
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Biological Activity

제품 설명

(S,S)-R116010 is a (S,S)-enantiomer of R116010 (HY-121500A). R116010 is a retinoic acid (RA) metabolism inhibitor and can inhibit hydroxylase CYP26. (S,S)-R116010 shows antitumor effects^[1]^[2].

IC₅₀ & Target

^[1]

CYP26

All RAR/RXR Isoforms :

All Cytochrome P450 Isoforms :

Chemical Information

CAS No. 355860-40-1
분자량 377.51
화학식 C₂₁H₂₃N₅S
SMILES

C[C@H](N(C)C)[C@H](C1=CC=C(NC2=NC3=CC=CC=C3S2)C=C1)N4C=CN=C4
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (284 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Wu W, et al. Enantioselective and Diastereoselective Construction of Chiral Amino Alcohols by Iridium-f-Amphox-Catalyzed Asymmetric Hydrogenation via Dynamic Kinetic Resolution. Org Lett. 2017 May 19;19(10):2548-2551. [Content Brief]

[2]. Armstrong JL, et al. Increasing the intracellular availability of all-trans retinoic acid in neuroblastoma cells. Br J Cancer. 2005 Feb 28;92(4):696-704. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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Amount: USD 0.00

Biological Activity
- 제품 설명
- IC₅₀ & Target
Chemical Information
순도&문서
References

상품명:
Cat. No.:
수량:
MCE Japan Authorized Agent:

상품명:
CAS No.:
Species:
Purity:
수량:

(S,S)-R116010

All RAR/RXR Isoforms

All Cytochrome P450 Isoforms

Biological Activity

제품 설명

IC50 & Target

Chemical Information

순도&문서

References

Calculators

Help & FAQs

(S,S)-R116010 Related Classifications

HY-121500 Related Classifications

Bioz

Keywords

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