M344 (GMP)
Based on 1 Customer Validation
M344 (GMP) (D 237) (GMP) is the GMP level of M344 (HY-13506). GMP level of small molecules can be used as auxiliary reagents in cell therapy. M344 is a kind of histone acetylation enzyme inhibitor.
For research use only. We do not sell to patients.
- CAS No.: 251456-60-7
- Formula: C16H25N3O3
- Molecular Weight:307.39
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| A-431 | IC50 |
2.3 μM
Compound: 23
|
Concentration required to inhibit the epidermoid A431 cell growth by 50%, P53 status of cell line used was wild-type.
Concentration required to inhibit the epidermoid A431 cell growth by 50%, P53 status of cell line used was wild-type.
|
[PMID: 11831887] |
| A549 | IC50 |
0.8 μM
Compound: 23
|
Concentration required to inhibit the lung A549 cell growth by 50%,P53 status of cell line used was wild-type.
Concentration required to inhibit the lung A549 cell growth by 50%,P53 status of cell line used was wild-type.
|
[PMID: 11831887] |
| HCT-116 | IC50 |
0.2 μM
Compound: 23
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Concentration required to inhibit the colon HCT116 cell growth by 50%,P53 status of cell line used was wild-type.
Concentration required to inhibit the colon HCT116 cell growth by 50%,P53 status of cell line used was wild-type.
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[PMID: 11831887] |
| HCT-116 | IC50 |
0.21 μM
Compound: 23
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Concentration required to inhibit the HCT116 cell growth by 50%.
Concentration required to inhibit the HCT116 cell growth by 50%.
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[PMID: 11831887] |
| LS174T | IC50 |
1.5 μM
Compound: 23
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Concentration required to inhibit the colon LS 174T cell growth by 50%,P53 status of cell line used was mutant-type.
Concentration required to inhibit the colon LS 174T cell growth by 50%,P53 status of cell line used was mutant-type.
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[PMID: 11831887] |
| NCI-H1299 | IC50 |
3.9 μM
Compound: 23
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Concentration required to inhibit the lung H1299 cell growth by 50%,P53 status of cell line used was wild-type.
Concentration required to inhibit the lung H1299 cell growth by 50%,P53 status of cell line used was wild-type.
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[PMID: 11831887] |
| SW-620 | IC50 |
0.7 μM
Compound: 23
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Concentration required to inhibit the colon SW 620 cell growth by 50%,P53 status of cell line used was mutant-type.
Concentration required to inhibit the colon SW 620 cell growth by 50%,P53 status of cell line used was mutant-type.
|
[PMID: 11831887] |
| T-24 | IC50 |
3.8 μM
Compound: 23
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Concentration required to inhibit the bladder T24 cell growth by 50%,P53 status of cell line used was wild-type.
Concentration required to inhibit the bladder T24 cell growth by 50%,P53 status of cell line used was wild-type.
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[PMID: 11831887] |
Chemical Information
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CAS No. 251456-60-7
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Appearance Solid
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Molecular Weight 307.39
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Formula C16H25N3O3
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Color White to off-white
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SMILES
O=C(NCCCCCCC(NO)=O)C1=CC=C(N(C)C)C=C1
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Synonyms
D 237 (GMP); MS 344 (GMP)
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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Data Sheet (264 KB)
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SDS (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
M344 (GMP) Related Classifications
HY-13506G Related Classifications
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