MT5-MMP-IN-1
MT5-MMP-IN-1 is a non-peptidic MT5-MMP (MMP-24) inhibitor with an IC50 of 6 μM. MT5-MMP-IN-1 interacts with the catalytic zinc ion of MT5-MMP via a hydroxamic acid zinc-binding group. MT5-MMP-IN-1 is applicable to the research of Alzheimer's disease.
For research use only. We do not sell to patients.
- Formula: C15H16N2O2
- Molecular Weight:256.30
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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MMP-24 6 μM (IC50) |
MT5-MMP-IN-1 (Compound 17) inhibits purified human MT5-MMP catalytic domain with an IC50 of 6 μM and achieves 59% inhibition at 10 μM, establishing it as a nonpeptidic micromolar hit for this enzyme[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Molecular Weight 256.30
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Formula C15H16N2O2
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SMILES
O=C(NO)CC(N)C1=CC=C(C2=CC=CC=C2)C=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)