Gliquidone-d6
Based on 1 Customer Validation
Gliquidone-d6 (AR-DF 26-d6) is the deuterated-labeled Gliquidone (HY-B1114). Gliquidone can bind to the pancreatic β-cells and increases insulin release to regulate blood glucose levels. Gliquidone significantly decreases LPS (HY-D1056)-induced proinflammatory responses and inhibits ERK/STAT3/NF-κB phosphorylation in BV2 microglial cells. Gliquidone can suppress microgliosis, microglial hypertrophy mediated by LPS, and proinflammatory cytokine COX-2 and IL-6 levels in murine model. Gliquidone also exhibits good anticancer activity in lung carcinoma cells. Gliquidone has antioxidant property. Gliquidone can be studied in research for type 2 diabetes and cancers.
For research use only. We do not sell to patients.
- Purity : 99.87%
- Formula: C27H27D6N3O6S
- Molecular Weight:533.67
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Protocols
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
Application
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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Unlabeled CAS 33342-05-1
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Appearance Solid
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Molecular Weight 533.67
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Formula C27H27D6N3O6S
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Color White to off-white
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SMILES
O=S(C1=CC=C(CCN(C(C(C([2H])([2H])[2H])(C([2H])([2H])[2H])C2=C3C=C(OC)C=C2)=O)C3=O)C=C1)(NC(NC4CCCCC4)=O)=O
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Synonyms
AR-DF 26-d6
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
In Vitro:
DMSO : 100 mg/mL (187.38 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (283 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.8738 mL | 9.3691 mL | 18.7382 mL | 46.8454 mL |
| 5 mM | 0.3748 mL | 1.8738 mL | 3.7476 mL | 9.3691 mL | |
| 10 mM | 0.1874 mL | 0.9369 mL | 1.8738 mL | 4.6845 mL | |
| 15 mM | 0.1249 mL | 0.6246 mL | 1.2492 mL | 3.1230 mL | |
| 20 mM | 0.0937 mL | 0.4685 mL | 0.9369 mL | 2.3423 mL | |
| 25 mM | 0.0750 mL | 0.3748 mL | 0.7495 mL | 1.8738 mL | |
| 30 mM | 0.0625 mL | 0.3123 mL | 0.6246 mL | 1.5615 mL | |
| 40 mM | 0.0468 mL | 0.2342 mL | 0.4685 mL | 1.1711 mL | |
| 50 mM | 0.0375 mL | 0.1874 mL | 0.3748 mL | 0.9369 mL | |
| 60 mM | 0.0312 mL | 0.1562 mL | 0.3123 mL | 0.7808 mL | |
| 80 mM | 0.0234 mL | 0.1171 mL | 0.2342 mL | 0.5856 mL | |
| 100 mM | 0.0187 mL | 0.0937 mL | 0.1874 mL | 0.4685 mL |
Gliquidone-d6 Related Classifications
HY-B1114S Related Classifications
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