Cholesterol

Taurohyocholic acid (THCA) sodium salt is a taurine-conjugated hyocholic acid. Taurohyocholic acid sodium salt is predictor of the efficacy of tyrosine kinase inhibitors combined withPD-1 inhibitors in hepatocellular carcinoma (HCC).

Cholesteryl palmitate is the main cholesterol ester found in human blephariol and has been used to form a stable tear film to study amphiphilic block copolymers as surfactants for dry eye syndrome. Cholesteryl palmitate can be used as a predictor of fetal lung maturity. Cholesteryl palmitate can be used as a prognostic biomarker for chronic interstitial pneumonia.

Cholesteryl arachidonate, a lipid, is an endogenous metabolite. Cholesteryl arachidonate has antibacterial activity.

Hydrocortisone acetate (Hydrocortisone 21-acetate) is a corticosteroid used to reduce swelling, itching and pain caused by minor skin irritations or hemorrhoids.

Brassicasterol is a metabolite of Ergosterol and has cardiovascular protective effects. Brassicasterol exerts anticancer effects in prostate cancer through dual targeting of AKT and androgen receptor signaling pathways. Brassicasterol inhibits HSV-1 (IC₅₀=1.2 μM) and Mycobacterium tuberculosis. Brassicasterol also inhibits sterol δ 24-reductase, slowing the progression of atherosclerosis. Brassicasterol is also a cerebrospinal fluid biomarker for Alzheimer's disease.

Cholesteryl behenate is a cholesterol ester associated with the neutral core of low density lipoprotein Receptor-LDL complexes are taken up by lysosomes and hydrolyzed to release cholesterol from the esters.

Cholesterol-PEG 600 is a synthetic cholesterol derivative and also a Aβ (1-42) binder. Cholesterol-PEG 600 promotes the fibrillogenesis of Aβ (1-42). Cholesterol-PEG 600 is applicable to the research of Alzheimer's disease.

Dehydroergosterol is a fluorescent cholesterol analog (Ex/Em = 325/375 nm) used in cholesterol transport, membrane structure research, and live-cell imaging. Unlike cholesterol, Dehydroergosterol contains three additional double bonds, an extra methyl group, and an ergosterol side chain, forming a conjugated system that produces intrinsic fluorescence. In its monomeric form, Dehydroergosterol exhibits excitation peaks at 310-311, 324, and 338-340 nm, as well as emission peaks at 354, 371-375, 390-394, and 414 nm; in its microcrystalline form, Dehydroergosterol shows enhanced excimer emission around 404 and 426 nm. Dehydroergosterol mimics the properties of cholesterol, integrates into membranes and lipoproteins, and localizes to organelles.

Cholesteryl acetate (Cholesterol 3-acetate) is a cholesterol ester that is exported from Saccharomyces cerevisiae via a Pry1-dependent mechanism. Cholesteryl acetate binds to the CAP superfamily protein Pry1 via interactions dependent on Pry1’s caveolin-binding motif.

Cholesteryl stearate is a compound belonging to the class of esters. It is a cholesterol ester commonly found in animal and plant sources. Cholesteryl stearate consists of two naturally occurring substances, cholesteryl alcohol and stearic acid. The combination of the two creates a stable compound that is commonly used in a variety of industrial and biomedical applications. Cholesteryl stearate is commonly used as a lubricant, thickener and emollient in cosmetic formulations such as lotions and creams. It is also used to produce certain types of polymers and plastics.

Cholesterol decanoate is an organic compound belonging to the class of esters. It is formed from the reaction between cholesterol and capric acid. Cholesterol decanoate has several applications in the pharmaceutical industry, particularly as a bioactive compound with potential research potential for improving a range of medical conditions, such as high cholesterol and inflammation-related diseases. Additionally, it has potential applications as a food additive to improve texture and stability.

Cholesteryl eicosapentaenoate (CE(20:5(5Z,8Z,11Z,14Z,17Z)), a cholesteryl ester, is a COX-1 and COX-2 inhibitor with IC₅₀ values of 14.6 μg/mL and 17.3 μg/mL, respectively. Cholesteryl eicosapentaenoate shows strong anti-inflammatory and antioxidant activities.

Cholesteryl heptadecanoate is a cholesteryl ester internal standard that accurately determines the concentration of free cholesterol in cells without hydrolyzing triglycerides. Cholesteryl heptadecanoate can be used for the quantitative determination of cholesteryl esters by GC or LC mass spectrometry.

BODIPY-cholesterol (solution) is an intrinsically lipophilic, and cell-permeable analog of cholesterol with a fluorescent BODIPY group. BODIPY-cholesterol can be used to monitor sterol uptake and inter-organelle sterol flux in cells. (Excitation/Emission: 505/515 nm) .
Solvent and concentration: DMSO: 1 mM

Cholesteryl n-butyrate is a cholesterol ester composed of cholesterol and butyrate, two naturally occurring substances. Cholesteryl n-butyrate can be used to synthesize solid lipid nanoparticles (SLNs) with inhibitory activity on the adhesion and migration of colon cancer cells, providing a delivery system for the anticancer drug butyrate.

Cholesteryl 11-eicosenoate is an ester product.

Cholesterylamine is a cationic lipid and cholesterol analog. Cholesterylamine mimics the membrane transport properties of cholesterol, cycles between the plasma membrane and early/recycling endosomes in mammalian cells, and serves as a platform for constructing synthetic cell surface receptors. Cholesterylamine can be used to prepare PLGA particles with surface charges for antigen binding. Cholesterylamine is applicable for drug delivery. Cholesterylamine is used in research on autoimmune diseases and allergies.

Cholesterol myristate is a natural steroid present in traditional Chinese medicine. Cholesterol myristate binds to several ion channels such as the nicotinic acetylcholine receptor, GABAA receptor, and the inward-rectifier potassium ion channel.

(R)-Chol-TPP a mitochondria targeting liposome ligand could be used in pH-redox responsive.

CE(16:1(9Z)) (16:1(9Z) CE) is a cholesterol ester. Plasma levels of cholesteryl palmitoleate are increased in ApoE^-/- mice exposed to cigarette smoke and in pediatric patients with biliary atresia. Cholesteryl palmitoleate has been used as a standard for the identification of cholesterol esters in human meibomian gland secretions.