PI3K-IN-47
PI3K-IN-47 (Compound 27) is a bivalent PI3K inhibitor (IC50: 0.44 nM for PI3Kα, 7.18 nM, 13.92 nM, 22.83 nM for PI3Kβ, PI3Kγ, PI3Kδ). PI3K-IN-47 induces cell cycle arrest in G1 phase, inhibits colony formation and cell migration. PI3K-IN-47 inhibits tumor growth in HGC-27 xenograft mice.
For research use only. We do not sell to patients.
- Formula: C50H46F4N8O8S2
- Molecular Weight:1027.07
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
0.44 nM for PI3Kα, 7.18 nM, 13.92 nM, 22.83 nM for PI3Kβ, PI3Kγ, PI3Kδ[1]
Chemical Information
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Molecular Weight 1027.07
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Formula C50H46F4N8O8S2
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SMILES
CC1=C2C=C(C3=CN=C(OC)C(NS(C4=CC=C(F)C=C4F)(=O)=O)=C3)C=C(OCCCCCCCCOC5=CC(C6=CN=C(OC)C(NS(C7=CC=C(F)C=C7F)(=O)=O)=C6)=CC8=C(C)N=CN=C58)C2=NC=N1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
PI3K-IN-47 Related Classifications
HY-149521 Related Classifications
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