(+)-Norcisapride
Based on 1 Customer Validation
(+)-Norcisapride (Ticalopride) is a potent 5-HT4 agonist and a 5-HT3 antagonist. (+)-Norcisapride has activity in animals models of constipation.
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- Pureté : 99.24%
- CAS No.: 202590-69-0
- Formule: C14H20ClN3O3
- Masse moléculaire:313.78
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Stockage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Activité biologique
Description
IC50 & Target
[1]|
5-HT4 Receptor |
5-HT3 Receptor |
Chemical Information
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CAS No. 202590-69-0
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Appearance Solid
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Masse moléculaire 313.78
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Formule C14H20ClN3O3
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Color White to off-white
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SMILES
O=C(N[C@H]1[C@@H](OC)CNCC1)C2=CC(Cl)=C(N)C=C2OC
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Synonyms
Ticalopride
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvant et solubilité
In Vitro:
DMSO : 40 mg/mL (127.48 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureté et documentation
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Fiche technique (271 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Instruction de manipulation (2659 KB)
Références
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.1869 mL | 15.9347 mL | 31.8695 mL | 79.6737 mL |
| 5 mM | 0.6374 mL | 3.1869 mL | 6.3739 mL | 15.9347 mL | |
| 10 mM | 0.3187 mL | 1.5935 mL | 3.1869 mL | 7.9674 mL | |
| 15 mM | 0.2125 mL | 1.0623 mL | 2.1246 mL | 5.3116 mL | |
| 20 mM | 0.1593 mL | 0.7967 mL | 1.5935 mL | 3.9837 mL | |
| 25 mM | 0.1275 mL | 0.6374 mL | 1.2748 mL | 3.1869 mL | |
| 30 mM | 0.1062 mL | 0.5312 mL | 1.0623 mL | 2.6558 mL | |
| 40 mM | 0.0797 mL | 0.3984 mL | 0.7967 mL | 1.9918 mL | |
| 50 mM | 0.0637 mL | 0.3187 mL | 0.6374 mL | 1.5935 mL | |
| 60 mM | 0.0531 mL | 0.2656 mL | 0.5312 mL | 1.3279 mL | |
| 80 mM | 0.0398 mL | 0.1992 mL | 0.3984 mL | 0.9959 mL | |
| 100 mM | 0.0319 mL | 0.1593 mL | 0.3187 mL | 0.7967 mL |