PROTAC BRD4 Degrader-38
PROTAC BRD4 Degrader-38 is a BRD4 PROTAC degrader with DC50s of 86 and 106 nM for the short and long isoforms of BRD4, respectively. PROTAC BRD4 Degrader-38 significantly induces the degradation of BRD4 by covalently engaging C232 of E3 ligase TRIM28.Pink: BRD4 ligand (HY-78695); Blue: E3 ligase ligand (HY-203082); Black: linker (HY-40172)
(Pink: BRD4 ligand (HY-78695); Blue: Ligands for E3 Ligase ligand (HY-203082); Black: linker (HY-40172)).
For research use only. We do not sell to patients.
- Formula: C31H30ClN7O4S
- Molecular Weight:632.13
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
All PROTACs Isoforms
More
Biological Activity
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BRD4 86 (BRD4-S nM (DC50) |
BRD4 106 (BRD4- nM (DC50) |
Chemical Information
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Molecular Weight 632.13
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Formula C31H30ClN7O4S
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SMILES
ClC1=CC=C(C2=N[C@@H](CC(NCCCNC(C3=CC=C(/C=C/[N+]([O-])=O)C=C3)=O)=O)C4=NN=C(C)N4C5=C2C(C)=C(C)S5)C=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
PROTAC BRD4 Degrader-38 Related Classifications
HY-175240 Related Classifications
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