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Cat. No.: HY-161387A

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(Rac)-EBET-590

(Rac)-EBET-590 is the racemate of EBET-590 (HY-161387). (Rac)-EBET-590 is a BET ligand. (Rac)-EBET-590 can serve as a ligand for the target protein in the synthesis of PROTAC BET degraders, such as (Rac)-EBET-1055 (HY-161346A). (Rac)-EBET-590 is suitable for cancer research.

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CAS No.: 3031540-02-7
Formule: C₂₆H₂₆N₄O₃
Masse moléculaire:442.51

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

(Rac)-EBET-590 Chemical Structure

CAS No.: 3031540-02-7

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- IC₅₀ & Target
Chemical Information
Pureté et documentation
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Description

IC₅₀ & Target^[1]

BET

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Chemical Information

CAS No. 3031540-02-7
Masse moléculaire 442.51
Formule C₂₆H₂₆N₄O₃
SMILES

OCC(OC1CC1)(C2=CC=CC=C2)C3=NC(N)=NC4=CC=C(C(C=C5C)=CN(C)C5=O)C=C43
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Instruction de manipulation (2659 KB)

Références

[1]. Nakazawa Y, et al. Delivery of a BET protein degrader via a CEACAM6-targeted antibody-drug conjugate inhibits tumour growth in pancreatic cancer models. Nat Commun. 2024 Mar 11;15(1):2192. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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- IC₅₀ & Target
Chemical Information
Pureté et documentation
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(Rac)-EBET-590

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Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

(Rac)-EBET-590 Related Classifications

HY-161387A Related Classifications