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Cat. No.: HY-117610

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Ro 31-8830

(Synonyms: Ro 32-0432 free base; Bisindolylmaleimide XI)

3 Cited Publications

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Based on 3 publication(s) in Google Scholar

Ro 31-8830 is an orally active, potent and selective inhibitor of protein kinase C with anti-inflammatory activity. Ro 31-8830 is promising for research of inflammatory disorders.

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CAS No.: 131848-98-1
Formule: C₂₈H₂₈N₄O₂
Masse moléculaire:452.55

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (274 KB)

Ro 31-8830 Chemical Structure

CAS No.: 131848-98-1

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique

Description

Ro 31-8830 is an orally active, potent and selective inhibitor of protein kinase C with anti-inflammatory activity. Ro 31-8830 is promising for research of inflammatory disorders^[1].

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Chemical Information

CAS No. 131848-98-1
Masse moléculaire 452.55
Formule C₂₈H₂₈N₄O₂
SMILES

O=C(NC1=O)C(C2=C3CC(CCN3C4=C2C=CC=C4)CN(C)C)=C1C5=CN(C6=C5C=CC=C6)C
Synonyms

Ro 32-0432 free base; Bisindolylmaleimide XI
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Publications (3)

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J Adv Res

Paeonol protects against doxorubicin-induced cardiotoxicity by promoting Mfn2-mediated mitochondrial fusion through activating the PKCε-Stat3 pathway. [Abstract]

2023 May:47:151-162. PMID: 35842187
Cell Mol Biol Lett

IP3R1-mediated MAMs formation contributes to mechanical trauma-induced hepatic injury and the protective effect of melatonin. [Abstract]

2024 Feb 2;29(1):22. PMID: 38308199
Cell Rep

KIF26B promotes bladder cancer progression via activating Wnt/β-catenin signaling in a TRAF2-dependent pathway. [Abstract]

2025 Apr 19;44(5):115595. PMID: 40253697

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (274 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Mulqueen MJ, et al. Oral, anti-inflammatory activity of a potent, selective, protein kinase C inhibitor. Agents Actions. 1992 Sep;37(1-2):85-9. [Content Brief]

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

Ro 31-8830

3 Cited Publications

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Publications (3)
Pureté et documentation
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Ro 31-8830

Publications Citing Use of MedChemExpress (MCE) Ro 31-8830

Voir tous les produits spécifiques à Isoform PKC

Activité biologique

Chemical Information

Publications (3)

Pureté et documentation

Références

Calculators

Help & FAQs

Ro 31-8830 Related Classifications

HY-117610 Related Classifications