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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
28 Results for "
anthrax
" in MedChemExpress (MCE) Product Catalog:
Products (28)
28 Results for "anthrax" in MCE Product Catalog:
14
Novobiocin (Albamycin; Cathomycin) is an orally active antibiotic and Hsp-90 antagonist that also inhibits the Polθ helicase/ATPase domain with IC50 values of 24 μM and 15-17 μM, respectively. Novobiocin binds to Hsp90, GyrB, and POLθ, inhibiting their ATPase activity and ssDNA binding. Novobiocin inhibits molecular chaperone function and DNA repair, and induces apoptosis and genomic instability. Novobiocin exhibits bactericidal and antiparasitic activities. Novobiocin inhibits tumor growth in vivo. Novobiocin is used for research on equine piroplasmosis, ovarian cancer, breast cancer, anthrax, and melioidosis .
14
14 Publications Verification
Synonyms: Albamycin sodium; Cathomycin sodium
7
7
1
1 Cited Publications
Cat. No.: HY-W157376
CAS No.: 155773-72-1
Target:
PAMAM Dendrimer G0.0 amine is a pore-forming channel antagonist, including anthrax toxin protective antigen 63 (PA63, IC50 = 231 nM) and C. botulinum C2 toxin subunit (C2IIa, IC50 = 940 nM). At concentrations of 10 and 20 µM, PAMAM Dendrimer G0.0 amine reduces C2 toxin-induced death in HeLa cells. Additionally, PAMAM Dendrimer G0.0 amine is a chelator of nickel. In complexes with polysulfone membrane-bound chitosan, PAMAM Dendrimer G0.0 amine selectively captures and stores carbon dioxide (CO2) in a gas-feed system. PAMAM Dendrimer G0.0 amine has been used in the synthesis of PAMAM Dendrimer G0.5 Carboxylate (CAS 339334-01-9) and PAMAM Dendrimer G1.0 Amine (CAS 142986-44-5). PAMAM Dendrimer G0.0 amine can be used in research related to infections, cancer, and drug delivery systems .
Cat. No.: HY-P9932
CAS No.: 1351337-07-9
Synonyms: ETI 204
Target:
Research Areas:
Cat. No.: HY-P9957
CAS No.: 565451-13-0
Synonyms: ABthrax
Cat. No.: HY-110147B
Purity: ≥99.0%
SSM-3 tetraTFA hydrate is a potent furin inhibitor with an EC50 of 54 nM. SSM-3 tetraTFA hydrate uses its positively charged guanidyl group to form strong electrostatic interactions with the negatively charged residues in the catalytic center of furin, thereby competitively occupying and blocking the active site. SSM-3 tetraTFA hydrate can be used in the research of anthrax and avian influenza .
Cat. No.: HY-110147A
CAS No.: 2320930-10-5
SSM-3 tetraTFA is a potent furin inhibitor with an EC50 of 54 nM. SSM-3 tetraTFA uses its positively charged guanidyl group to form strong electrostatic interactions with the negatively charged residues in the catalytic center of furin, thereby competitively occupying and blocking the active site. SSM-3 tetraTFA can be used in the research of anthrax and avian influenza .
Cat. No.: HY-P85628
Synonyms: anthrax PA; anthrax toxins translocating protein; PA 83; PA; PA83; Pag; PagA; Protective antigen.
Cat. No.: HY-P81315
Synonyms: Protective antigen
Cat. No.: HY-P81315A
Synonyms: Protective antigen
Cat. No.: HY-179376
Anti-virulence factor-IN-3 (Compound 21) is a covalent β-aminosulfinyl type anthrax edema factor (EF) inhibitor, with a Ki value of 0.44 μM. Anti-virulence factor-IN-3 generates an active ethylene sulfinyl intermediate, which forms an irreversible covalent bond with the Lys residue at the active center of EF, permanently inhibiting the adenylate cyclase activity of EF. Anti-virulence factor-IN-3 effectively inhibits the cAMP production induced by EF, with an EC50 value of 0.15 μM. Anti-virulence factor-IN-3 can be used for research on anthrax Infection .
Cat. No.: HY-P76153
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ANTXR2; FLJ31074; ANTXR Cell Adhesion Molecule 2; anthrax Toxin Receptor 2, Isoform CRA_c; CMG-2; anthrax Toxin Receptor; CMG2; ANTXR2 Protein; anthrax Toxin Receptor 2; HFS; Capillary Morphogenesis Gene 2 Protein; ISH; Capillary Morphogenesis Protein 2;
Species:
Mouse
Source:
HEK293
Cat. No.: HY-P76151
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: ANTXR2; FLJ31074; ANTXR Cell Adhesion Molecule 2; anthrax Toxin Receptor 2, Isoform CRA_c; CMG-2; anthrax Toxin Receptor; CMG2; ANTXR2 Protein; anthrax Toxin Receptor 2; HFS; Capillary Morphogenesis Gene 2 Protein; ISH; Capillary Morphogenesis Protein 2;
Species:
Human
Source:
HEK293
Cat. No.: HY-P76152
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: ANTXR2; FLJ31074; ANTXR Cell Adhesion Molecule 2; anthrax Toxin Receptor 2, Isoform CRA_c; CMG-2; anthrax Toxin Receptor; CMG2; ANTXR2 Protein; anthrax Toxin Receptor 2; HFS; Capillary Morphogenesis Gene 2 Protein; ISH; Capillary Morphogenesis Protein 2;
Species:
Mouse
Source:
HEK293
Cat. No.: HY-P700656
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ANTXR2; FLJ31074; ANTXR Cell Adhesion Molecule 2; anthrax Toxin Receptor 2, Isoform CRA_c; CMG-2; anthrax Toxin Receptor; CMG2; ANTXR2 Protein; anthrax Toxin Receptor 2; HFS; Capillary Morphogenesis Gene 2 Protein; ISH; Capillary Morphogenesis Protein 2;
Species:
Human
Source:
HEK293
Cat. No.: HY-189475
CAS No.: 706772-75-0
NADs-IN-2 is a NADSYN1 inhibitor. NADs-IN-2 also binds to the NaAD subsite within the active site of bacterial NADs, thereby inhibiting enzymatic function. NADs-IN-2 can be used in research related to anthrax and cancer .
Cat. No.: HY-110147
CAS No.: 922732-52-3
SSM-3 is a potent furin inhibitor with an EC50 of 54 nM. SSM-3 uses its positively charged guanidyl group to form strong electrostatic interactions with the negatively charged residues in the catalytic center of furin, thereby competitively occupying and blocking the active site. SSM-3 can be used in the research of anthrax and avian influenza .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
