Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
188 Results for "
Cortical
" in MedChemExpress (MCE) Product Catalog:
Products (188)
188 Results for "Cortical" in MCE Product Catalog:
1
1 Cited Publications
Target:
Research Areas:
CGP7930 (3-(3’,5’-Di-tert-butyl-4’-hydroxy) phenyl-2, 2-dimethylpropanol) is a positive metabotropic GABAB receptor allosteric modulator. CGP7930 enhances the inhibitory effect of l-baclofen on the oscillatory activity of cultured cortical neurons .
1
1 Cited Publications
Cat. No.: HY-P2031
CAS No.: 26645-35-2
Target:
1
1 Cited Publications
Cat. No.: HY-N0307
CAS No.: 114902-16-8
Category:
Triterpenes Terpenoids Acanthopanax senticosus (Rupr. et Maxim.) Harms Plants Araliaceae Extract
Target:
1
1
1 Cited Publications
Cat. No.: HY-N0695
CAS No.: 58546-55-7
Synonyms: Gomisin-B; Wuweizi ester-B; Schisantherin-B
1
1 Cited Publications
Target:
LY310762 is a selective 5-HT1D receptor antagonist with a Ki value of 249 nM for the guinea pig receptor. LY310762 blocks presynaptic 5-HT1D autoreceptors and enhances potassium-stimulated [ 3H]5-HT outflow from guinea pig cortical slices. LY310762 abolishes the inhibitory effect of 5-CT (HY-135555)/L-694,247 (HY-101208) on sympathetic nerve-induced renal vasoconstriction mediated by prejunctional 5-HT1D receptors. LY310762 potentiates the increase in extracellular 5-HT concentration induced by Fluoxetine (HY-B0102). LY310762 is used in research related to depression and diabetic nephropathy .
Target:
Research Areas:
Equilin (7-Dehydroestrone) is an important member of the large group of oestrogenic substances and is chemically related to menformon (oestrone). Equilin increases the growth of cortical neurons via an NMDA receptor-dependent mechanism .
Target:
Cat. No.: HY-P2426
CAS No.: 118102-98-0
Target:
Research Areas:
Cat. No.: HY-120017
CAS No.: 134564-82-2
Synonyms: MD-370503
Target:
Research Areas:
Befloxatone (MD-370503) is an orally active, selective and reversible inhibitor of Monoamine Oxidase A (MAO-A) (IC50=4 nM). Befloxatone increases the tissue level of monoamine, striatal dopamine and cortical norepinephrine. Befloxatone has antidepressant potential .
Target:
Research Areas:
Immepip dihydrobromide is a H3 agonist. Immepip dihydrobromide can reduce cortical histamine release. Immepip dihydrobromide can be used for the research of neurological diseases .
Cat. No.: HY-N8249
CAS No.: 168706-29-4
Target:
Cat. No.: HY-101321
CAS No.: 151070-83-6
Target:
Research Areas:
Immepip is a H3 agonist. Immepip can reduce cortical histamine release. Immepip can be used for the research of neurological diseases .
Synonyms: Glucosilsteviol
Target:
Research Areas:
Steviolmonoside (Glucosilsteviol) is a structural analogue of steviol. Steviolmonoside decreases glucose production and inhibits oxygen uptake in rat renal cortical tubules .
Cat. No.: HY-P4811
CAS No.: 112160-82-4
Target:
Research Areas:
Cat. No.: HY-12294
CAS No.: 459836-30-7
Synonyms: NVP-AAM077
Research Areas:
PEAQX (NVP-AAM077) is an orally active and selective NMDA antagonist, with IC50 values of 270 nM and 29.6 μM for hNMDAR 1A/2A and hNMDAR 1A/2B, respectively. PEAQX can promote the activation of caspase-3 and induce cell apoptosis in cortical striatal slice cultures .
Target:
Research Areas:
Azacosterol (20.25-Diazacholesterol), also known as Diazasterol, acts as a DHCR24 inhibitor and initiates a cascade of reactions in cortical neurons after being administered orally or via intraperitoneal injection.
Target:
Research Areas:
IEM-1754, a dicationic adamantane derivative, is a potent blocker of open channels of native ionotropic glutamate receptors including quisqualate-sensitive receptors in insect muscles, NMDAR in cultured rat cortical neurons, and AMPAR in freshly isolated hippocampal cells. IEM-1754 shows anticonvulsant potency in vivo .
Cat. No.: HY-177888
CAS No.: 111142-68-8
Target:
Research Areas:
Lc2Cer(d18:1, 22:0) is a lactosylceramide containing d18:1, C22:0 ceramides. Lc2Cer(d18:1, 22:0) can be used for renal cortical epithelial cell research .
Target:
Research Areas:
WAY 208466 dihydrochloride is a potent and selective 5-HT6 receptor agonist (EC50=7.3 nM for the human 5-HT6 receptor). WAY-208466 dihydrochloride elevates cortical GABA levels in rat frontal cortex . WAY 208466 dihydrochloride exhibits antidepressant and anxiolytic-like effects .
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
