579 Results for "

Wnt

" in MedChemExpress (MCE) Product Catalog:
Products (579)

579 Results for "Wnt" in MCE Product Catalog:

21
21 Cited Publications
Cat. No.: HY-A0293
CAS No.: 3546-41-6
Synonyms: Pyrvinium embonate
Target:  

Wnt

Research Areas:  

Cancer

Pyrvinium pamoate is an FDA-approved antihelmintic agent that inhibits WNT pathway signaling.
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21
21 Cited Publications
Cat. No.: HY-N0020
CAS No.: 82854-37-3
Echinacoside, one of the phenylethanoids isolated from the stems of Cistanche deserticola, effectively inhibits Wnt/β-catenin signaling. Echinacoside elicits neuroprotection by activating Trk receptors and their downstream signal pathways. Antiosteoporotic activity .
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20
20 Cited Publications
Cat. No.: HY-15721
CAS No.: 108409-83-2
Purity:  99.88%
Target:  

PPAR Wnt β-catenin

Research Areas:  

Cancer

FH535 is an inhibitor of Wnt/β-catenin and PPAR with anti-tumor activities .
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20
20 Cited Publications
Cat. No.: HY-16665
CAS No.: 677331-12-3
Target:  

Wnt

Research Areas:  

Cancer

iCRT 14 is a novel potent inhibitor of β-catenin-responsive transcription (CRT), with IC50 of 40.3 nM against Wnt responsive STF16 luciferase.
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19
19 Cited Publications
Cat. No.: HY-N0279
CAS No.: 18956-16-6
Synonyms: Cardamomin; Alpinetin chalcone
Cardamonin can be found from cardamom, and can target various signaling molecules, transcriptional factors, cytokines and enzymes. Cardamonin can inhibit mTOR, NF-κB, Akt, STAT3, Wnt/β-catenin and COX-2. Cardamonin shows anticancer, anti-inflammatory, antimicrobial and antidiabetic activities .
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17
17 Cited Publications
Cat. No.: HY-101090
CAS No.: 1956356-56-1
Purity:  ≥98.0%
Target:  

Wnt β-catenin

Research Areas:  

Cancer

KYA1797K is a potent and selective Wnt/β-catenin inhibitor with an IC50 of 0.75 µM.
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16
16 Cited Publications
Cat. No.: HY-122816
CAS No.: 854847-61-3
Purity:  98.44%
HLY78, a Lycorine (HY-N0288) derivative, is a potent activator of the Wnt/β-catenin signaling pathway. HLY78 targets the DIX domain of Axin and promotes the Axin-LRP6 (lipoprotein receptor-related protein 6) association, thus promoting LRP6 phosphorylation and Wnt signal transduction. HLY78 can be used for subarachnoid hemorrhage (SAH) research .
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14
14 Cited Publications
Cat. No.: HY-123071
CAS No.: 1206604-29-6
Purity:  99.24%
Target:  

Wnt

Research Areas:  

Cancer

Box5 is a potent Wnt5a antagonist. Box5 inhibits Wnt5a signaling and inhibits Wnt5a-mediated Ca 2+ release. Box5 inhibits cell migration. Box5 has the potential for the research of melanoma .
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14
14 Cited Publications
Cat. No.: HY-123071A
Purity:  99.24%
Target:  

Wnt

Research Areas:  

Cancer

Box5 TFA is a potent Wnt5a antagonist. Box5 TFA inhibits Wnt5a signaling and inhibits Wnt5a-mediated Ca 2+ release. Box5 TFA inhibits cell migration. Box5 TFA has the potential for the research of melanoma .
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13
13 Cited Publications
Cat. No.: HY-11035
CAS No.: 1123231-07-1
Purity:  99.11%
Target:  

β-catenin Wnt

Research Areas:  

Cancer

WAY-262611 is a Wnt/β-Catenin agonist that increases bone formation rate with an EC50 of 0.63 μM in TCF-Luciferase assay. WAY-262611 is also a Dkk1 inhibitor .
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13
13 Cited Publications
Cat. No.: HY-N0889
CAS No.: 481-46-9
Ginkgetin, a biflavone, is isolated from Ginkgo biloba leaves. Ginkgetin exhibit anti-tumor, anti-inflammatory, neuroprotective, anti-fungal activities. Ginkgetin is also a potent inhibitor of Wnt signaling, with an IC50 of 5.92 μΜ .
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12
12 Cited Publications
Cat. No.: HY-103705
CAS No.: 901751-47-1
Purity:  98.05%
Target:  

Wnt Apoptosis

Research Areas:  

Cancer

iCRT3 is an inhibitor of both Wnt and β-catenin-responsive transcription.
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12
12 Cited Publications
Cat. No.: HY-101130
CAS No.: 113906-27-7
Purity:  99.93%
Target:  

Wnt β-catenin Apoptosis

Research Areas:  

Cancer

PNU-74654 is an inhibitor of Wnt/β-catenin pathway with an IC50 of 129.8 μM in NCI-H295 cell.
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12
12 Cited Publications
Cat. No.: HY-10456
CAS No.: 303162-79-0
Purity:  99.76%
Target:  

p38 MAPK Casein Kinase Wnt

Research Areas:  

Inflammation/Immunology

TAK-715 is an orally active and potent p38 MAPK inhibitor with IC50s of 7.1 nM, 200 nM for p38α and p38β, respectively. TAK-715 inhibits casein kinase I (CK1δ/ε) to regulate activation of Wnt/β-catenin signaling. TAK-715 shows good significant efficacy in a rat arthritis model .
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11
11 Cited Publications
Cat. No.: HY-P7155A
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: DKK1; Dickkopf 1 Homolog (Xenopus Laevis); Dickkopf Wnt Signaling Pathway Inhibitor 1; Dickkopf 1 Homolog; SK; Dickkopf-1 Like; DKK-1; Dickkopf-1; Dickkopf-Related Protein 1; HDkk-1; Dickkopf-Like Protein 1; Dkk-1; Dickkopf (Xenopus Laevis) Homolog 1
Species:  
Human
Source:  
HEK293
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10
10 Cited Publications
Cat. No.: HY-114321
CAS No.: 2305372-67-0
Purity:  99.72%
Target:  

Wnt

Research Areas:  

Cancer

Wnt/β-catenin agonist 1 (compound 3f) is a Wnt/β-catenin signalling pathway agonist, with an EC50 of 0.27 μM .
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10
10 Cited Publications
Cat. No.: HY-109049
CAS No.: 1467093-03-3
Purity:  98.85%
Synonyms: SM04690; Lorecivivint
Target:  

Wnt

Research Areas:  

Inflammation/Immunology Cancer

Adavivint (SM04690; Lorecivivint) is a potent and selective inhibitor of canonical Wnt signaling, with an EC50 of 19.5 nM via a high-throughput TCF/LEF-reporter assay in SW480 colon cancer cells .
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10
10 Cited Publications
Cat. No.: HY-B1640
CAS No.: 58-54-8
Synonyms: Etacrynic acid
Ethacrynic acid has anti-inflammatory and anticancer activity. Ethacrynic acid is an orally active diuretic. Ethacrynic acid is an inhibitor of glutathione S-transferase (GSTs) and Wnt signaling pathways. Ethacrynic acid is a radiosensitizer. Ethacrynic acid can inhibit airway smooth muscle (ASM) contraction in mice. Ethacrynic acid can increase the outflow of aqueous humor from the eye for the study of glaucoma .
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9
9 Cited Publications
Cat. No.: HY-P70453B
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Wnt3A; Wnt Family Member 3A; Wingless-Type MMTV Integration Site Family, Member 3A; Protein Wnt-3a
Species:  
Human
Source:  
HEK293
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9
9 Cited Publications
Cat. No.: HY-N1411
CAS No.: 58479-68-8
Platycodin D is a saponin isolated from Platycodon grandiflorus, acts as an activator of AMPKα, with anti-obesity property. WNT/β-catenin pathway mediates the anti-adipogenic effect of platycodin D .
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