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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
623 Results for "
biologically active
" in MedChemExpress (MCE) Product Catalog:
Products (623)
623 Results for "biologically active" in MCE Product Catalog:
7
7 Cited Publications
Cat. No.: HY-D0143B
CAS No.: 207671-44-1
6
6 Cited Publications
Synonyms: L-5,6,7,8-Tetrahydrofolic acid; L-Tetrahydrofolic acid
Category:
Human Gut Microbiota Metabolites Microorganisms Metabolic Disease Amino acids Endogenous metabolite Disease Research Fields
Target:
6
5
5 Cited Publications
Cat. No.: HY-N2292
CAS No.: 151870-74-5
Category:
Natural Products Orchidaceae Extract Plants Anoectochilus Disease Research Fields Inflammation/Immunology
Target:
5
5 Cited Publications
Synonyms: AKR-501; E5501; YM477
Target:
Research Areas:
Avatrombopag (AKR-501) is an orally active, nonpeptide thrombopoietin (TPO) receptor agonist (EC50=3.3 nM). Avatrombopag mimics the biological activities of TPO. Avatrombopag increases platelet production by activating the intracellular signaling system, and promotes production of platelets and megakaryocytes from hemopoietic precursor cells. Avatrombopag is a substrate of cytochrome P450 (CYP) 2C9 and CYP3A .
5
5 Cited Publications
Synonyms: AKR-501 maleate; E5501 maleate; YM477 maleate
Research Areas:
Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
Avatrombopag (AKR-501) maleate is an orally active, non-peptide thrombopoietin receptor (TPO receptor) agonist (EC50: 3.3 nM). Avatrombopag maleate mimics the biological activity of TPO. Avatrombopag maleate increases platelet production by activating intracellular signaling systems and promotes the production of platelets and megakaryocytes from hematopoietic precursor cells. Avatrombopag maleate is a substrate for cytochrome P450 (CYP) 2C9 and CYP3A .
5
5 Cited Publications
Synonyms: AKR-501 hydrochloride; E5501 hydrochloride; YM477 hydrochloride
Target:
Research Areas:
Avatrombopag (AKR-501) hydrochloride is an orally active, nonpeptide thrombopoietin (TPO) receptor agonist (EC50=3.3 nM). Avatrombopag hydrochloride mimics the biological activities of TPO. Avatrombopag hydrochloride increases platelet production by activating the intracellular signaling system, and promotes production of platelets and megakaryocytes from hemopoietic precursor cells. Avatrombopag hydrochloride is a substrate of cytochrome P450 (CYP) 2C9 and CYP3A .
5
5 Cited Publications
Cat. No.: HY-112482A
CAS No.: 2624336-92-9
Target:
Research Areas:
ABT-702 hydrochloride is a potent, orally active, and selective adenosine kinase (AK) inhibitor with an IC50 of 1.7 nM. ABT-702 hydrochloride shows >1300-fold selectivity for AK over other biological targets, including cyclooxygenases-1 and -2. ABT-702 hydrochloride attenuates inflammation in diabetic retinopathy by increasing free adenosine levels. ABT-702 hydrochloride shows analgesic and anti-inflammatory effects in vivo. ABT-702 hydrochloride can be used for diabetic retinopathy research .
5
5 Cited Publications
Cat. No.: HY-112482
CAS No.: 214697-26-4
Target:
Research Areas:
ABT-702 (Adenosine Kinase Inhibitor) is a potent, orally active, and selective adenosine kinase (AK) inhibitor with an IC50 of 1.7 nM. ABT-702 shows >1300-fold selectivity for AK over other biological targets, including cyclooxygenases-1 and -2. ABT-702 attenuates inflammation in diabetic retinopathy by increasing free adenosine levels. ABT-702 shows analgesic and anti-inflammatory effects in vivo. ABT-702 can be used for diabetic retinopathy research .
4
4 Cited Publications
Target:
Research Areas:
MLS0315771 is a potent and biologically active competitive phosphomannose isomerase (MPI) inhibitor, with an IC50 ~1 μM and a Ki of 1.4 μM.
4
3
3
Category:
Immune System Disorder Ketones, Aldehydes, Acids Other Diseases Disease markers Endocrine diseases Endogenous metabolite Disease Research Fields Cardiovascular System Disorder
Target:
3
3 Cited Publications
Cat. No.: HY-76082A
CAS No.: 28874-51-3
Target:
3
3 Cited Publications
Synonyms: ADW742; GSK 552602A; ADW
Target:
Research Areas:
NVP-ADW742 (ADW742) is an orally active, selective IGF-1R tyrosine kinase inhibitor with an IC50 of 0.17 μM. NVP-ADW742 inhibits insulin receptor (InsR) with an IC50 of 2.8 μM. NVP-ADW742 induces pleiotropic antiproliferative/proapoptotic biologic sequelae in tumor cells .
3
3 Cited Publications
Cat. No.: HY-N2464
CAS No.: 34612-38-9
Synonyms: Amylotetraose; Fujioligo 450; α-1,4-Tetraglucose
3
3 Cited Publications
Cat. No.: HY-N1401
CAS No.: 112246-15-8
2
2
2 Cited Publications
Synonyms: 2-Aminothiazole; 2-Thiazolylamine
Target:
Research Areas:
Aminothiazole (2-Aminothiazole), a typical heterocyclic amine, is a precursor for the synthesis of biologically active molecules including sulfur agents, biocides, fungicides, antibiotics, dyes and chemical reaction accelerators .
2
2 Cited Publications
Cat. No.: HY-P5397A
Target:
Research Areas:
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
