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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
359 Results for "
Intestinal cells
" in MedChemExpress (MCE) Product Catalog:
Products (359)
359 Results for "Intestinal cells" in MCE Product Catalog:
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1 Cited Publications
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5-Acetylsalicylic acid is the derivate of Aspirin (HY-14654), with anti-inflammatory property. 5-Acetylsalicylic acid is the active metabolite of Sulfasalazine (HY-14655) and its production is regulated by beneficial bacteria in the gut but is confined to the intestinal tract. 5-Acetylsalicylic acid exhibits a mild cytotoxicity effect on B16F10 cells. 5-Acetylsalicylic acid can be used for the study of inflammatory bowel disease (IBD) such as ulcerative colitis (UC) .
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1 Cited Publications
Cat. No.: HY-W127512
CAS No.: 546-18-9
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5β-Cholanic acid is a hydrophobic modifier used to modify polymer carriers. 5β-Cholanic acid can improve the acid stability, cell penetration efficiency and drug sustained release ability of nanocarriers, and optimize the oral effectiveness of delivered molecules. 5β-Cholanic acid can covalently bind to Glycol chitosan (GC) to form a GC-CA conjugate, which optimizes the hydrophobic anchoring ability of nanoparticles and enables them to be stably adsorbed on the surface of PLGA nanoparticles. Such nanoparticles can resist dissociation in the gastric acid environment and maintain positive charge to enhance endocytic uptake by intestinal epithelial cells (such as Caco-2 cells). 5β-Cholanic acid can be used in the development of drug delivery systems .
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1 Cited Publications
Cat. No.: HY-N2830
CAS No.: 21499-24-1
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1 Cited Publications
Cat. No.: HY-W015635
CAS No.: 2179-57-9
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1 Cited Publications
Cat. No.: HY-N1916
CAS No.: 63644-62-2
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Flavonols Flavonoids Myrtaceae Phenols Polyphenols Plants Disease Research Fields Syzygium aromaticum Cancer
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1 Cited Publications
Cat. No.: HY-P1108
CAS No.: 681260-70-8
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18:1 BMP (S,S) ammonium (18:1 LBPA (S,S)) is a monounsaturated fatty acid phospholipid. 18:1 BMP (S,S) ammonium reduces lysosomal lipid peroxidation and inhibits the ionizing radiation-induced elevation of intracellular labile ferrous ion (Fe 2+) levels. 18:1 BMP (S,S) ammonium can be used in studies related to ionizing radiation-induced intestinal injury .
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Cat. No.: HY-B1953
CAS No.: 111988-49-9
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Thiacloprid is an orally active neurotoxic insecticide and also a nAChR agonist. Thiacloprid reduces the viability of healthy cells, depletes reduced glutathione, and increases MDA levels, thereby inducing cytotoxicity and oxidative stress damage. In practical applications, Thiacloprid has lower acute toxicity to honeybees than other compounds of the same class such as Imidacloprid (HY-B0838), but it still significantly impairs the learning and memory function, immune capacity and survival status of honeybees. Thiacloprid induces intestinal microbial dysbiosis and reduces survival rate in middle-aged honeybees, increases the risk of premature collapse in bumblebee colonies, and significantly decreases the final colony weight and reproductive output. Thiacloprid is used in broad-spectrum agricultural pest control, often alone or in combination with Deltamethrin (HY-B1971), and meets the pest management needs of various crops including potatoes, cabbages, various fruits and vegetables, and nuts .
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1 Cited Publications
Cat. No.: HY-N2376
CAS No.: 35775-49-6
Category:
Flavones Plants Oroxylum indicum (Linn.) Bentham ex Kurz Flavonoids Monophenols Labiatae Other Diseases Phenols Bignoniaceae Disease Research Fields Medicago truncatula Gaertn.
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1 Cited Publications
Cat. No.: HY-19695
CAS No.: 62284-79-1
Synonyms: L-p-Bromotetramisole oxalate; 6-Bromolevamisole oxalate
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Sebetralstat (KVD900) is an orally active and selective plasma kallikrein inhibitor, with an IC50 of 6.0 nM and a Ki of 3.0 nM against the human target. Sebetralstat binds to the active site of plasma kallikrein, inducing a conformational flip of Trp215 to form a U-shaped conformation; its P1 group interacts with the S1 pocket through hydrophobic interactions and displacement of high-energy water molecules, independent of the Asp189 ionic bond. Sebetralstat inhibits plasma kallikrein-kinin system activation in whole plasma, rapidly relieves laryngeal and abdominal attack symptoms of hereditary angioedema (HAE-C1INH), and reduces attack severity. Sebetralstat can be used in research related to hereditary angioedema (HAE) .
Cat. No.: HY-D1736
CAS No.: 158757-82-5
Cat. No.: HY-W011053
CAS No.: 165450-17-9
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Neotame is a derivative of Aspartame (HY-B0361) and is a flavor enhancer and low-caloric, non-nutritive, high-intensity artificial sweetener that is 7000-13,000 times sweeter than sugar. Neotame causes intestinal epithelial cell death at high concentrations. Neotame induces Apoptosis of Caco-2 cells .
Cat. No.: HY-W145518
CAS No.: 9000-69-5
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Zea mays L. Polysaccharides Gramineae Other Diseases Plants Disease Research Fields Saccharides
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Cat. No.: HY-W001160
CAS No.: 1953-54-4
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
