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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
249 Results for "
shape-selective methylation
" in MedChemExpress (MCE) Product Catalog:
Products (249)
249 Results for "shape-selective methylation" in MCE Product Catalog:
Cat. No.: HY-176822
CAS No.: 2650530-02-0
Research Areas:
SGC-BRDVIII-NC (Compound 35) is a negative control compound of SMARCA2/4 and PB1 bromodomain (BRD) inhibitor. SGC-BRDVIII-NC completely abolishes protein-ligand binding capacity with the methylation of the phenolic hydroxyl moiety. SGC-BRDVIII-NC can be used for adipogenesis research .
Cat. No.: HY-111130R
CAS No.: 91-80-5
Research Areas:
Methapyrilene (Standard) is the analytical standard of Methapyrilene (HY-111130). This product is intended for research and analytical applications. Methapyrilene is a histamine antagonist, a pyridine chemical with anticholinergic activity. Methapyrilene can cause target organ-specific epigenetic alterations, such as a decrease in DNA methylation levels. Methapyrilene induces hepatocellular carcinoma in rats .
Cat. No.: HY-113138R
CAS No.: 2140-69-4
Synonyms: N3-Methyluridine (Standard)
Category:
Cat. No.: HY-N19725
CAS No.: 51787-31-6
Target:
Cat. No.: HY-P2254
Target:
Research Areas:
Cat. No.: HY-W014004
CAS No.: 174664-65-4
Synonyms: CBHA
m-Carboxycinnamic acid bishydroxamide (CBHA) is a histone deacetylase inhibitor. m-Carboxycinnamic acid bishydroxamide modulates histone acetylation sites, alters DNA methylation and epigenetic status, increases global histone acetylation, alleviates transcription repression, and facilitates chromatin remodelling. m-Carboxycinnamic acid bishydroxamide can be used for the research of cloned embryo development and epigenetic regulation .
Cat. No.: HY-W1006754
CAS No.: 1973504-60-7
Target:
Research Areas:
NNMT-IN-7 is a nicotinamide N-methyltransferase (NNMT) inhibitor with an IC50 of 505.7 μM against human targets. NNMT-IN-7 inhibits the catalytic activity of NNMT, an enzyme responsible for mediating N-methylation modification of endogenous and exogenous xenobiotics. NNMT-IN-7 can be used in research related to obesity and type 2 diabetes .
Cat. No.: HY-P87932
Synonyms: ASC, CARD5, TMS1, PYCARD, Apoptosis-associated speck-like protein containing a CARD, hASC, Caspase recruitment domain-containing protein 5, PYD and CARD domain-containing protein, Target of methylation-induced silencing 1
Cat. No.: HY-P10143
CAS No.: 99828-55-4
Synonyms: Ac-Pro-Leu-Gly-[(S)-2-mercapto-4-methyl-pentanoyl]-Leu-Gly-OEt
Synonyms: (S)-2-Hydroxyglutaric acid
Cat. No.: HY-P86234
Synonyms: PYCARD; ASC; CARD5; TMS1; Apoptosis-associated speck-like protein containing a CARD; hASC; Caspase recruitment domain-containing protein 5; PYD and CARD domain-containing protein; Target of methylation-induced silencing 1
Cat. No.: HY-P3066
CAS No.: 77453-01-1
Synonyms: d(CH2)5Tyr(Et)VAVP
Target:
Research Areas:
Cat. No.: HY-124124R
CAS No.: 114-33-0
Category:
Cat. No.: HY-E70584
Target:
Research Areas:
Recombinant APOBEC3A (A3A) Protein is a single-domain cytosine deaminase with antiviral activity that deaminates cytosine to uracil, thereby specifically detecting DNA methylation levels. Recombinant APOBEC3A (A3A) Protein is recombinantly expressed in E.coli and is suitable for bisulfite-free 5-hydroxymethylcytosine whole-genome sequencing (such as ACE-Seq), cytosine deamination, etc .
Cat. No.: HY-E71728
Research Areas:
Methylated porcine trypsin is a serine protease, which is divided into two categories: heterologously methylated type and homogeneously recombinantly methylated type. Methylated porcine trypsin hydrolyzes the C-terminal peptide bonds of lysine and arginine, and can block autolytic sites via reductive methylation modification of lysine residues, thereby inhibiting autoproteolysis. Methylated porcine trypsin is applicable to protein-related research .
Cat. No.: HY-W004883
CAS No.: 1193-71-1
Synonyms: 5A-DMP
Target:
Research Areas:
3-Amino-4,6-dimethylpyridine (5A-DMP) is a UHRF1 inhibitor that targets the Arg-binding cavity site within the UHRF1 TTD domain. 3-Amino-4,6-dimethylpyridine disrupts the interaction between UHRF1 and LIG1, interfering with DNA methylation, and can be utilized in cancer research .
Cat. No.: HY-W012426
CAS No.: 32231-06-4
Synonyms: MDBP
Target:
Research Areas:
1-Piperonylpiperazine (MDBP) is metabolized by demethylenation and subsequent methylation to N-(4-hydroxy-3-methoxybenzyl)piperazine followedby partial glucuronidation or sulfation. 1-Piperonylpiperazine can alter the disposition and metabolism of 3,4-methylenedioxymethamphetamine (MDMA) in the brain and in peripheral organs. 1-Piperonylpiperazine can inhibit the MDMA-induced neurotoxicity .
Cat. No.: HY-W015114
CAS No.: 63512-50-5
Synonyms: (S)-2-Hydroxyglutaric acid disodium
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
